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Biomedical subjects

R D Eaton

Publications and source records attributed to R D Eaton.

At least 19 recordsLinked to original sources

Respiratory function impairment and cardiopulmonary consequences in long-time residents of the Canadian Arctic.

Spirometry, roentgenography and electrocardiography were performed during community health surveys in 1976-78 in 176 Inuit and other long-time residents of the northeastern (Arctic Bay) and western (Inuvik) Canadian Arctic, and the results were related to age, ethnic origin, occupation and history of climatic exposure, smoking and hospitalization for tuberculosis. In Arctic Bay the young men showed excellent respiratory function, normal-sized pulmonary arteries and normal electrocardiograms, but abnormalities of all three types were increasingly frequent and severe after age 25. The forced mid-expiratory flow (FMF) fell to less than 50% of the norm by age 40, and dilatation of the pulmonary artery, hypertrophy of the right ventricle, right bundle branch block and a pseudoinfarction pattern on the ECG were frequently associated. In contrast, the men in Inuvik, an urbanized centre, maintained above normal respiratory function until age 40, and the FMF and pulmonary artery diameter remained normal in the older men except for Inuit and white trappers over 60 years old who had run fox trap lines along the Arctic coast in the 1920s and 30s. These data suggest that inhalation of extremely cold air at maximum ventilation may be a prime factor in the chronic obstructive lung disease of Inuit hunters, whereas smoking has only a minor role and hospitalization for tuberculosis appears to protect from rather than contribute to this disorder.

Adolescent↗

Prevalence of rabies virus in foxes trapped in the Canadian Arctic.

Brains and salivary glands of 521 trapped arctic foxes (Alopex lagopus) submitted from four different settlement areas in the Northwest Territories were examined for rabies by the standard fluorescent antibody and mouse inoculation tests. Rabies antigen was present in 44 of 201 (21.9%) brains from foxes trapped in the Sachs Harbour area, but submissions from Cambridge Bay (127), Spence Bay (93) and Gjoa Haven (100) were negative. Virus was also present in salivary glands from 43 (97.7%) of these 44 positive foxes. The arctic fox continues to be the main wildlife reservoir of rabies in the Canadian Arctic and foxes in the prodromal stage of the disease pose a particular threat to the trapper. Preexposure vaccination should always be a consideration in this occupational group.

Animals↗

Some intestinal parasites of Arctic fox, Banks Island, N. W. T.

Small intestinal parasitology of 50 trapped Arctic fox taken on Banks Island, The Northwest Territories, showed a prevalence of Taenia crassiceps (78%), Toxascaris leonina (60%), Echinococcus multilocularis (2%) and Coccidia (2%). Attention is drawn to the absence of Toxocara sp. and of Uncinaria sp.

Animals↗

Parasites of dogs from Indian settlements in northwestern Canada: a survey with public health implications.

A total of 959 faecal samples were obtained from dogs in 12 native communities in Northern Saskatchewan, Central and Northern Alberta and the Northwest Territories. All samples were examined using a flotation technique. Samples from an area of endemic human amoebic infections were also examined by a formol-ether sedimentation method. Eighteen necropsies were performed. Entamoeba histolytica cysts were recovered from dog faeces at Loon Lake, Saskatchewan. Toxocara canis had low incidence in Saskatchewan and Central Alberta, and appeared to be almost non-existent further North. Toxascaris leonina was found in all areas surveyed. Canine hookworm infections were plentiful in all areas, the highest incidence being recorded from Northern Alberta and Northwest Territories. Many Taenia (or Echinococcus) infections were found consistently in all areas. Only one infection with Dipylidium caninum was discovered.Metorchis conjunctus infections were found to be common in the Saskatchewan reserves. Infections with Diphyllobothrium sp. were found in all communities with access to good fishing. One specimen of Dioctophyma renale was recovered at necropsy. Infections with parasites of no known zoonotic importance such as Trichuris, Alaria and Isospora species were also recorded.

Amebiasis↗