[Jorge Lobo mycosis. Contribution to its experimental study. Inoculation of man and laboratory animals and immunologic research].
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Biomedical subjects
Publications and source records attributed to R D Azulay.
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A new case of erythema multiforme is described, characterized by multiforme eruption of erythematous papules, plaques and occasional bullous lesions. The acute stage lasts several seeks, then atrophy is noted. The face appears senile. Histopathologically, the lesions show erythema multiforme in the acute phase; in the atrophic stage, a disappearance of the elastic fibers was observed.
Keloidal blastomycosis (Lobo's disease) is reported in a 34-year-old man from the Brazilian Amazon area. His left ear and posterior auricular region were involved. He is the eighth of 99 patients known to have lymph node involvement.
The number of B and T lymphocytes were determined in the blood of 35 Brazilian patients with leprosy: 19 lepromatous (L), 9 borderline (B), 4 tuberculoid (T), and 3 indeterminate (I) and also in a control group of 30 normal individuals. The results, were as follows. B lymphocytes, no differences between the patients with hanseniasis and the control group; T lymphocytes, there was an evident depletion in the patients with L compared to the control group and patients with T; and the average of T lymphocytes in B and I was lower than that seen in the control group and in patients with T. Despite this alteration they approach to what is found in the patients with T and the control group.
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