Prevention and management of ovarian hyperstimulation syndrome.
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Biomedical subjects
Publications and source records attributed to R Curson.
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The results of this study show that ultrasound measurements by the transabdominal and transvaginal routes are statistically comparable and reproducible between observers. The somewhat larger standard deviations found with transabdominal scanning suggest that the transvaginal route may be more accurate in the daily monitoring of follicular development.
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212 consecutive pregnancies are reviewed in previously infertile women. 96 had conceived following treatment, 21 in a "rest cycle" after treatment, 60 during investigations and 35 before investigations were started. There were 25 miscarriages (11.8%), 13 following hormone treatment. There were 7 multiple pregnancies, 2 sets of triplets and 5 sets of twins. The multiple pregnancy rate with Clomiphene was 3.9% and with gonadotrophins 30%. Pregnancy after the first trimester was normal, 82 (44%) were induced, 79% laboured for less than 12 hours. Spontaneous vaginal delivery occurred in 107 patients (55%), forceps delivery in 34%, breach 5.6% and caesarean section 6.1%. Only 20 babies weighed less than 2500 grams (10.5%) and 168 (88%) had an apgar score greater than 5. These infertile patients were matched with a control group of our normal obstetric population. There was no significant difference between the control and infertile patients except for a higher induction rate (p less than 0.0005) and higher forceps rate (p less than 0.001) in the infertile patients. We conclude that pregnancy following infertility is associated with a higher spontaneous miscarriage rate, but otherwise is normal.
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