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Biomedical subjects

R Cortesini

Publications and source records attributed to R Cortesini.

At least 163 records · Page 9Linked to original sources
PubMedDate not supplied

Immunological reactivity of peripheral lymphocytes in kidney transplant patients.

The in vitro lymphocyte response to mitogens (PHA, PWM) and specific antigens (PPD, LPS, histocompatibility antigens), as well as their capacity to form spontaneous SRBC rosettes, was evaluated in 24 renal transplant patients; of these, 13 were studied both before and after kidney graft. The results of our tests, compared to the range of values obtained from healthy controls, show that continuous immunosuppressive therapy does not significantly depress the in vitro mitotic potentiality of lymphocytes in spite of greatly reduced levels of circulating T cells. The in vitro escape of lymphocytes from the action of immunosuppressive drugs frustrated the aim of calibrating the immunodepressive therapy for each patient. A better understanding of the immunosuppression in an individual will perhaps be obtained from a more prolonged observation of the in vitro lymphocyte reactivity in a larger number of patients.

Adolescent↗
PubMedDate not supplied

The organizational model of the interregional transplant agency Organizzazione Centro-Sud Trapianti.

In Italy, all donation and transplant activities were officially disciplined in 1999 by the law 91 of April 1, 1999. This law enacted a coordinator-based model of transplantation, instituted the National Center for Transplantation (Centro Nazionale Trapianti-CNT), and endorsed the existing interregional transplant agencies (ITA), such as the Nord Italia Transplant program (NITp), the Associazione InterRegionale Trapianti (AIRT), and the Organizzazione Centro-Sud Trapianti (OCST). Within its borders each ITA has adopted its own organizational model; there is no overt centralized control exerted by the CNT according to the law 91/1999. The aim of the current work is to report on the organizational model adopted by OCST, the ITA gathering the Italian regions of Abruzzo, Basilicata, Calabria, Campania, Latium, Molise, Sardinia, Sicily, and Umbria.

Humans↗