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Biomedical subjects

R Contreras

Publications and source records attributed to R Contreras.

At least 145 records · Page 8Linked to original sources
PubMedDate not supplied

Hepatic fascioliasis: case report and review.

A well documented case of hepatic fascioliasis (HF), successfully treated with triclabendazole, is reported. Predominant clinical manifestations were fever, marked eosinophilia and abdominal pain. Triclabendazole was given as two single oral doses of 10 mg/kg each. Neither side effects nor clinical or parasitological relapses were seen after three months of follow up. Based on this experience and few other similar reports in the literature, triclabendazole might be a valid therapeutical alternative in the treatment of human fascioliasis.

Administration, Oral↗
PubMedDate not supplied

Randomized trial of fructosamine home monitoring in patients with diabetes.

CONTEXT: Recognition of the importance of glycemic control in type 2 diabetes has generated interest in developing ways to improve such control. Levels of fructosamine, 1-amino-1-deoxyfructose, are highly correlated with those of hemoglobin A1c (HbA1c) and can be monitored in the home. DESIGN: Randomized trial. PARTICIPANTS: 140 adult patients with HbA1c values of 8% or greater were recruited to the trial through referral from physicians and a direct mailing to potentially eligible persons. INTERVENTION: Weekly home fructosamine monitoring in addition to daily glucose monitoring. Control patients monitored daily glucose only. Both groups of patients were contacted regularly by telephone and were given the same instructions on diet and exercise. OUTCOME: Measures of glycemic control 3 and 6 months after randomization. RESULTS: No significant difference was found between the two groups in the mean absolute decrease of HbA1c levels at 3 months (0.5% in the fructosamine group vs. 0.8% in the control group; P > 0.2), and the difference favored the control group at 6 months (0.7% fructosamine vs. 1.2% control; P = 0.04). Both groups had a statistically significant improvement in glycemic control. CONCLUSIONS: The addition of home fructosamine monitoring to routine glucose monitoring did not improve glycemic control.

Adolescent↗
PubMedDate not supplied

Aortic bacterial endarteritis.

Micotic aneurisms are very rare. They are produced as a consequence of a bacterial infection of the endartery. They are divided into "primary", or those of an unknown septic focus, and "secondary" to bacterial endocarditis, to intravascular in infection or to infection located in a neighboring region. Two cases of the National Institute of Cardiology of Mexico are presented, with "primary" micotic aneurysm, which is the least frequent. One of them was because of bacterial endarteritis located in the thoracic aorta, an extremely rate entity. Due to the frequent rupture of these aneurysm with a very high mortality, emphasis is placed on the convenience of rapid surgical treatment of patients diagnosed.

Adolescent↗
PubMedDate not supplied

[Presence of antibodies against Toxoplasma gondii in adolescents from the African continent].

It was determined the presence of antibodies anti-T. gondii in young, 13-16 year old, belonging to Republic Arab Saharaui; Popular Republic of Angola; Ethiopia and Republic of Ghana. From a total of 707 sera analyzed, the 71.43% of them showed the presence of specific antibodies. The prevalence of antibodies did not differ significantly (P > 0.05) between males and females in Angola and Republic Arab Saharaui. It was found a significant difference (P < 0.0001) among countries.

Adolescent↗
PubMedDate not supplied

[Inhibition of Mucor rouxii growth by synthetic substances].

Mucor rouxii cells were used to examine the possible antimycotic activities of four substances: phenolamines, phenylendiamine and quinone. These substances are original structures recently synthesized. Assays in plates showed that 10(-2) M of phenolamines and phenylendiamines give rise to halos of growth inhibition. Assays in liquid media using 10(-4) M of substances showed 100% inhibition of spore germination. Specifically, the phenylendiamine showed 49% inhibition on development of mycelium. In these cells the calcofluor distribution changes, suggesting alterations in cell wall. No inhibition of growth was found using the quinone. The activity for substances were evaluated using standard antifungal benomyl. On this basis, the substance phenylendiamine it is an antimycotic active. The mechanism of action is not presently known.

Aniline Compounds↗