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Biomedical subjects

R Conroy

Publications and source records attributed to R Conroy.

53 records · Page 3Linked to original sources
PubMed1988

Secular changes in mortality among survivors of unstable angina and myocardial infarction.

Seven hundred and ninety-four males under 60 years who survived a first episode of unstable angina or myocardial infarction by 28 days were admitted to St. Vincent's Hospital between 1965 and 1981 inclusive. They were followed for at least 4 years: 1-, 2- and 4-year mortality during the follow-up period did not alter significantly during the 17 years. Significant changes did take place over time in the severity of the coronary attacks and in the risk profile of the patients. A greater number of complicated infarcts occurred in the later years and there were fewer smokers and more hypertensives. There was a significant increase over time in the number of initial cigarette smokers who stopped after the coronary attack. Changing methodology made secular changes in cholesterol levels difficult to interpret.

Adult↗
PubMed1985

HTLV-III env gene products synthesized in E. coli are recognized by antibodies present in the sera of AIDS patients.

The envelope gene of HTLV-III, the retrovirus directly linked to AIDS, encodes a protein of 856 amino acids. Our sequence analysis of the cloned HTLV-III (HXB-3) env gene and its comparison with other isolates reveal significant divergence, especially in the external portion of this protein. A large segment of the env gene (1800 bp) was inserted into the expression vector pEV-vrf3, and a corresponding 68 kd protein, which encompasses both the extracellular and the membrane-associated regions of the native protein, was produced in E. coli. Several smaller polypeptides, which appear to be internal initiation products, were also produced. All 50 AIDS patient sera obtained from different locations in the United States specifically recognized the bacterially synthesized envelope proteins, as judged by Western blots. This suggests that these proteins will be useful for the diagnosis of HTLV-III infection and possibly as a vaccine against AIDS.

Acquired Immunodeficiency Syndrome↗
PubMed1985

Categories of depression: reported life events in a controlled design.

In a case control study, 32 onset cases of depression, separated into PSE-CATEGO Categories N and R, were compared with individually matched symptom free general practice attenders. Combining both categories of depressives together a significantly greater number reported an Undesirable Life Event and a Threatening Life Event in the six months prior to onset, compared with their matched controls. Significantly more CATEGO R (retarded or endogenous) depressives reported an Independent Threatening event than their matched controls. These findings do not support the view that depression secondary to a major life event is more likely to be mild in character.

Adolescent↗
PubMed1982

Social networks, attachments and support in minor affective disorders: a replication.

Significant deficiencies in personal social networks and social support in non-psychotic psychiatric out-patients have been reported by Henderson ad his colleagues. In a replication study, 50 non-psychotic psychiatric out-patients were compared with 50 matched controls. Patients reported spending less time in social interaction, but more time in unpleasant interaction during the previous week; they also had fewer attachment figures, close relatives and good friends and fewer social contacts than controls. However, the separate analysis of Neurotic and Retarded depressives (using the Present State Examination) failed to replicate all these findings in the Retarded depressives. It is concluded that these associations are confirmed in neurotic patients, but that the more severe depressive disorders require further investigation.

Adolescent↗
PubMed1977

The value of arteriography before abdominal aneurysmectomy.

We believe preoperative angiography is a safe procedure with current technics. The importance of the lateral aortogram in identifying mesenteric or celiac artery stenosis is emphasized. Sixty per cent of all patients studied showed some abnormal arteriographic finding. Significant abnormalities include (1) associated arteriosclerotic occlusions, (2) multiple aneurysms, and (3) anomalous vessels. As we consider this preoperative data of great importance in the planning of the total operation, we strongly recommend the routine use of aortography as described in evaluating all nonruptured abdominal aortic aneurysms.

Aged↗
PubMedDate not supplied

Teaching infant resuscitation skills to mothers.

This paper describes the evaluation of a program designed to teach basic infant resuscitation skills to mothers during the period of postnatal hospitalization. Data collected from participants before and immediately after the program, and at six months, follow-up indicated that knowledge of resuscitation techniques had moderately improved, however there was a substantial increase in participants' confidence and an associated reduction in anxiety. An additional aspect of the evaluation was to identify any logistical problems; data obtained from postnatal midwifery staff indicated none were evident. It was concluded that the Infant Resuscitation Education Program should be implemented for all mothers of newborn infants.

Female↗
PubMedDate not supplied

Employing a practice nurse: what sort of GP?

The general practitioners employing all 102 nurses known to be practising as practice nurses in the Republic of Ireland were sent a questionnaire for completion anonymously. A response rate of 51% was obtained. Practices employing practice nurses were found to be mostly single handed (28/52) in a town/rural setting (39/52) and participating in the General Medical Services (GMS) Scheme (49/51)*. A substantial minority of practices (16/51)* derived more than 75% of their income from the GMS. Eighty five percent of practices felt that their practice "gained or would gain financially" through the employment of a practice nurse. (* = one non-respondent)

Employment↗
PubMedDate not supplied

A comparative study of neonates' umbilical cord management .

The aim of this study was to establish the effect of treating neonates' umbilical cords with chlorhexidine 0.5% in alcohol 70% on cord separation time and to observe the clinical and microbiological consequences of not treating the cords of healthy neonates. The treated group contained 466 babies whose cords were treated with chlorhexidine, 424 babies were not treated. Microbiological colonisation patterns of the cords of babies in both groups were monitored both for purposes of this investigation and to ensure that no untoward consequences resulted from non-treatment. The research showed that treatment prolonged separation time by 1.7 days, which was significant at the level of p = 0.000, and that normal colonisation was delayed in the treated group.

Chlorhexidine↗