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Biomedical subjects

R Colebunders

Publications and source records attributed to R Colebunders.

At least 181 records · Page 10Linked to original sources

Prosthetic valve endocarditis due to methicillin-resistant Staphylococcus epidermidis and Micrococcus species successfully treated with rifampicin combined with other antibiotics.

Two patients with prosthetic valve endocarditis due to methicillin-resistant Gram-positive cocci (Staphylococcus epidermidis and Micrococcus spp.) are described. They were successfully treated with rifampicin combined first with an aminoglycoside and later with co-trimoxazole or co-trimoxazole plus vancomycin. The addition of rifampicin to these antibiotics resulted in enhanced serum bactericidal activity. High doses of rifampicin (1200-1800 mg) for 7-8 weeks did not cause any serious side-effect. Surgery was not required. During surveillance for more than 2 years endocarditis did not recur.

Adult↗

Determination of free thyroid hormones and their binding proteins in a patient with severe hyperthyroidism (thyroid storm?) and thyroid encephalopathy.

A patient with severe hyperthyroidism (thyroid storm?) and thyroid encephalopathy is described. During her illness only a slightly raised level of total thyroxine and a normal level of total triiodothyronine was found in contrast with very high levels of free thyroid hormones. Very low levels of thyroxine binding globulin, albumin and low levels of thyroxine binding prealbumin in contrast with nearly normal values of T3 resin uptake were observed. All parameters of thyroid function returned to normal after therapy.

Adult↗

A patient with testis seminoma, sarcoidosis, and neutropenic enterocolitis.

Seminoma and sarcoidosis do not seem to be associated diseases, judging from epidemiologic data. The presence of these two diseases in the patient whose case is reported may have been coincidental. It was observed, however, that when the testis tumor appeared in this patient, the longstanding sarcoid lesions significantly increased. The patient developed neutropenic enterocolitis after chemotherapy for a non-hematologic malignancy.

Adult↗

Adult Still's disease caused by Yersinia enterocolitica infection.

Clinical and biologic features of adult Still's disease developed in a patient who had high antibody titers against Yersinia enterocolitica during his illness. Immunocomplexes containing antibodies against Yersinia antigens were isolated at the beginning of the disease. Yersinia was not isolated from blood or stool specimens probably because we observed the patient during the secondary phase of the disease.

Adult↗

Group B streptococcus arthritis.

Serious infections with group B streptococcus (streptococcus agalactiae) are rare in adults. A 81-year-old patient with cirrhosis who developed a septic arthritis due to this germ, is described. Only eleven cases of group B streptococcal arthritis have been previously reported.

Aged↗

Pulmonary haematoma caused by oral anticoagulant therapy. Report of a case.

During a poorly controlled warfarin treatment, a 51-year-old man developed bleeding in various organs. He presented a pulmonary haematoma with the radiologic appearance of a pulmonary nodule. In the literature we found only one report of a pulmonary haematoma with a similar presentation caused by anticoagulant therapy.

Diagnosis, Differential↗