Biomedical subjects
R Clayton
Publications and source records attributed to R Clayton.
Isolation and identification of chick lens crystallin messenger RNA.
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Immunological analysis of lens protein structure.
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A study of roentgenologic criteria for rheumatoid arthritis of the cervical spine.
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Sustainability of prevention.
This paper outlines the guidelines for sustaining prevention and makes suggestions for getting from the field's current status to greater levels of permanence for prevention. The paper begins by reviewing the status of prevention, then focuses on major considerations for achieving sustainability, including two processes of institutionalization, comprehensive programming and professionalism.
Prevention and health promotion on the international scene: the need for a more effective and comprehensive approach.
The last decade has shown a boom in international networks and projects in health promotion and prevention. The growth of international collaboration is considered to be of crucial importance for the future development of the field. Several arguments are discussed in support of a further expansion of collaboration across countries and regions. The author criticizes the current lack of effectiveness in international collaboration in health promotion and prevention and identifies main barriers to effective collaboration. To make significant progress in research, evidence-based programs and policies, and their implementation worldwide, the creation of a comprehensive system of functional and effective linkages is needed across the core task areas, across disciplines, across system levels, and across countries and cultures. The quality of prevention and health promotion research as well as its impact on the health of communities depends on the degree to which research institutes and other stakeholders are embedded in an effective network of interorganizational and international relationships capable of performing a broad range of essential and functionally related tasks. It is critical that the dynamics of effective international collaboration become a legitimate subject of prevention and health promotion science.
Experimental models to investigate the pathology of antisperm antibodies: approaches and problems.
Antisperm antibodies (ASA) can interfere with sperm function and fertilization. But we still know relatively little about the specific mechanisms that elicit an auto-immune response and we have a poor appreciation of the profile of ASA that lead to antibody-mediated infertility in the male. This brief review explores some of the experimental models, the current approaches and the problems associated with investigations of ASA.
Contact allergy to spearmint oil in a patient with oral lichen planus.
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Treatment and prevention of use and abuse of illegal drugs: progress on interventions and future directions.
State-of-the-art downstream interventions are generally successful for half of drug-abusing clients. But, only one in four abusers actually receives treatment. In the midstream, one setting (schools), one type of prevention ("one size fits all"), and a limited age-range focus (adolescence and preadolescence) have predominated. Accumulating evidence casts doubt on the effectiveness of widely disseminated school-based prevention approaches, although theory-based programs that emphasize skills training and adjunctive parent and neighborhood interventions fare better. Newer pursuits include intervening very early with higher risk children and expanding to primary health care settings and workplaces. Popular but unproven community approaches need more rigorous evaluation. Upstream national and state public policy and environmental interventions should be reexamined in light of their success for preventing tobacco and alcohol use.
Managing alcohol problems and risky drinking.
While overall alcohol consumption and alcohol-related automobile deaths have declined, rates of alcohol dependence, liver cirrhosis, and alcohol-related problems remain high among adults, and binge drinking continues as a major health risk for high school and college students. Some individual-level downstream interventions have been evaluated with sufficient rigor to recommend widespread dissemination, and widened availability of new pharmacotherapies could further increase effectiveness. Midstream population-based programs, such as screening and brief interventions in hospitals and managed care organizations, may have greater public health impact than tertiary treatment because of early identification and low cost. Upstream programs and policies that place limits on alcohol availability (e.g., higher legal purchasing age) have the greatest potential to reduce morbidity and mortality at the least cost to society.
Extracorporeal circulation material evaluation: microemboli.
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Limitations in the use of HIAC for product particle counting.
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