Search PubMed⌕ Search

Biomedical subjects

R Cheli

Publications and source records attributed to R Cheli.

At least 127 records · Page 7Linked to original sources
PubMedDate not supplied

Clinical, diagnostic and therapeutic aspects of caecal displacement in calves fed reconstituted milk.

On the basis of a large number of cases the occurrence of displacement of the caecum is reported in calves fed reconstituted milk. This displacement, a classification of which is given, occurs with the movement of the caecum into the left half of the abdomen in contrast to what occurs in animals fed a different diet. After a description of the various clinical and diagnostic aspects, details are given of the surgical technique used for treatment, and an aetiopathogenic hypothesis is formulated to explain the disease process.

Animal Feed↗
PubMedDate not supplied

Congestive and hemorrhagic lesions of duodenal mucosa. Critical evaluation.

In 34 patients congestive, hemorrhagic lesions were detected by endoscopy. It was considered that trauma was not responsible for these lesions. In all of the patients except four, histology showed no inflammatory reaction. Most of the patients were hypochlorhydric and one was achlorhydric. Serum gastrin levels appeared within a normal range under fasting and stimulated conditions. Twenty-four patients were followed up two years later. Only 1 patient had developed a duodenal ulcer. The endoscopic picture appeared unmodified in the reendoscopized patients. It is concluded that the hemorrhagic lesions of the duodenum may result from local vascular disorders without any inflammation.

Adult↗
PubMedDate not supplied

Stimulated gastrinemia, parietal cell mass and stimulated acid secretion in autonomous chronic gastritis: Helicobacter pylori influence.

BACKGROUND/AIMS: In the present experience, an evaluation has been carried out of stimulated gastrinemia, parietal cell mass, and acid secretion in the course of a paradigmatic condition, such as autonomous chronic gastritis, in order to reveal possible changes induced by the presence of Helicobacter Pylori (HP). MATERIALS AND METHODS: We evaluated 153 patients with chronic gastritis of the antrum and/or body fundus, in different combinations not associated with peptic pathology. RESULTS: In the group of subjects with antral superficial chronic gastritis associated with normal body-fundic mucosa or with body-fundic superficial chronic gastritis, about 40% of the subjects in the HP positive group show gastrinemia values which are higher than the norm. The evaluation of parietal cell and stimulated acid secretion yielded no differences between the HP positive and HP negative groups: it emerges that these parameters vary exclusively according to the histologic state of the body-fundic mucosa. In the patients group with hypergastrinemia, the study has revealed no variations in parietal cell mass and acid secretion. CONCLUSION: Evidently the increase in gastrinemia in these subjects was not important enough to induce an increase in parietal cell mass and acid secretion. It emerges how the presence of HP does not imply substantial changes on the gastric cyto-functional parameters: these variations depend mainly on the histologic state of the gastric mucosa.

Adult↗
PubMedDate not supplied

Levosulpiride in functional dyspepsia: a multicentric, double-blind, controlled trial.

Abnormalities in gastrointestinal motility have been reported in a substantial proportion of patients with functional dyspepsia, supporting the use of prokinetic drugs for treatment of dyspeptic symptoms. To evaluate efficacy and safety of levosulpiride in short-term treatment, 1298 patients were enrolled in a double-blind multicentric study carried out in 45 Italian Gastroenterology Departments. Patients were randomly assigned to either levosulpiride (25 mg tid), domperidone (10 mg tid), metoclopramide (10 mg tid) or placebo (1 tablet tid) for 4 weeks. Patients were selected on the basis of: a) occurrence in the last 4 weeks of at least 5/10 selected symptoms (anorexia, nausea, vomiting, upper abdominal pain, postprandial bloating, abdominal fullness, early satiety, belching, heartburn, regurgitation), severity of which should reach/exceed a total score of 8, as assessed by a specific scale ranging from 0 (absent) to 3 (severe); b) normal results of routine biochemical, ultrasound and endoscopic examinations. In addition, each patient subjectively evaluated efficacy of treatment by a visual analogue scale. Significant improvement was recorded for all symptoms at days 10 and 28 in all groups (p < 0.001), but levosulpiride was significantly (p < 0.01) superior to domperidone, metoclopramide and placebo both in the overall clinical improvement scale as well as in a subgroup of symptoms (postprandial bloating, epigastric pain, heartburn). Active treatments and placebo were comparable as far as concerns occurrence of side-effects (12-20%) including galactorrhoea, breast tenderness and menstrual changes.

Adolescent↗