Biomedical subjects
Publications and source records attributed to R Charles.
Two fatal cases of the fulminant type of isovaleric acidemia are described. Attention is drawn to the existence of two forms of the disease, the severe "Newman" type, occurring in the first week of life and the milder "Tanaka" type, with a later onset. The importance of ruling out isovaleric acidemia in any newborn infant with acidosis is emphasized.
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OBJECTIVES: To profile those over 65 yr admitted to an acute geriatric medical service. To identify and assess their undernutrition risk and quantify the nutritional intervention they received. METHODS: Forty-nine consecutive admissions were recruited, 23 various parameters were assessed. A diagnosis of undernutrition was made according to a specifically designed flow chart. RESULTS: Eighty-four per cent of recruits were at risk of undernutrition on admission and 80 per cent were moderately to severely at risk. There was deterioration from baseline nutritional status in 29 per cent of previously well nourished patients with hospitalization. In the undernourished group, an improvement and/or stasis from baseline was achieved in 75 per cent, with intervention. CONCLUSIONS: The risk of undernutrition on admission to hospital and during treatment is an indicator of the need for nutrition services and nutritional screening for all acute medical services for older people.
To analyze the changes in rat-liver carbamoyl-phosphate synthase (Cpase) protein levels during ontogenesis, these levels were determined by means of two independent methods, i.e. radioimmunoassay and densitometric assay. During normal development the changes in catalytic activity of Cpase are accompanied by equivalent changes in the quantities of enzyme protein. We have obtained evidence for the existence of a perinatal Cpase which is immunochemically different from adult Cpase as immunoreactivity of Cpase decreases in the perinatal period and remains constant thereafter.
Repairs of pelvic fistulas using abdominal, vaginal, and laparoscopic approaches have been described. In the present case report, we describe our experience with the laparoscopic repair of a uteroperitoneal fistula.