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Biomedical subjects

R Casigliani

Publications and source records attributed to R Casigliani.

16 recordsLinked to original sources
PubMed1989

[Acute phase proteins as markers of septic risk in surgical patients].

A heterogeneous group of surgery patients at septic risk was studied through monitoring of acute phase proteins (APP). Plasma levels of 8 acute phase proteins (C-reactive, alpha-1 antitrypsin, fibrinogen, ceruloplasmin, transferrin, albumin, prealbumin, alpha-2 macroglobulin) were measured in the pre- and postoperative period of septic surgery patients suffering from disease processes in various sites and with different aetiopathogenesis. The experiment is related to some interesting research proposed by authors in the Shock Physiopathology Study Centre of the Catholic University of Rome and their results. The constant finding of increased values of PCR, fibrin, cerul, alpha-1 Tryp in the septic risk surgery patient and their normalisation following treatment is particularly significant. In these same cases, a depression or, depending on circumstances, normal findings of Transf, alpha-2 Macro, Albu and Prealbu were observed. The results point to the practical utility an high reliability of APP changes as markers of septic risk.

Acute-Phase Proteins↗
PubMed1989

[The so-called spontaneous hematoma of the anterior rectus abdominis reproducing syndromes of acute surgical abdomen].

Personal experience of spontaneous haematoma on the anterior straight muscles of the abdomen over 15 years is reported. True spontaneous haematoma on the anterior straight muscles of the abdomen are extremely rare, even exceptional and must be distinguished from those haematomas, improperly called spontaneous that are, in fact, clearly traumatic in origin. Personal observation suggests that true spontaneous haematoma is the expression of a pathological rupture of the muscle and/or the epigastric blood vessels that in its turn reflects a serious basic pathology.

Abdomen, Acute↗
PubMed1988

Multicentric reticulohistiocytosis. Report of three cases with the evaluation of tissue proteinase activity.

Three cases of multicentric reticulohistiocytosis showing typical clinical, histologic, and ultrastructural findings are reported. In one, gastric cancer occurred; in the other two cases, severe polyarthritis was the only detectable internal involvement. The serine proteinases, urokinase and tissue-type plasminogen activator, were evaluated both with the autohistographic technique and spectrophotometric assay in lesional skin and synovia. Urokinase levels appeared grossly increased in the lesional synovia and moderately increased in the lesional skin. We suggest that urokinase, presumably released by the activated proliferating histiocytes, may play a major role in the extracellular matrix degradation leading to erosion of cartilage and adjacent bone in multicentric reticulohistiocytosis.

Adult↗