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Biomedical subjects

R C Thompson

Publications and source records attributed to R C Thompson.

474 records · Page 27Linked to original sources
PubMedDate not supplied

Load testing of geometric and polycentric total knee replacements.

Static loading of implanted geometric and polycentric knee replacements was conducted in order to define fixation characteristics and load capabilities of the prostheses and the bone prostheses interface. Failures occurred in some specimens at load levels normally encountered across the knee joint during ambulation. Disruption of the tibial bone-cement interface and crushing of the tibial plateau were the modes of failure. There was no failure on the femoral side of the joint. The major determinants of stress failure suggested by this study were: (1) the tibial bone strength, (2) the design of the geometric and polycentric tibial component, and (3) method of component implantation.

Aged↗
PubMedDate not supplied

Cortisone induced bone changes and its response to lipid clearing agents.

Thirty-two rabbits were used experimentally to study the effect of cortisone in bone, lungs, kidneys, and liver. Cortisone does induce abnormal increases in the serum cholesterol, fatty metamorphosis of the liver and the fatty emboli of the subchondral vessels of the femoral heads. Clofibrate therapy appeared to modify the cortisone induced changes as evidenced by a lower serum cholesterol level, prevention or lessening of the increase in the marrow fat cell size. This might significantly improve microcirculation of the femoral head.

Animals↗
PubMedDate not supplied

Pathologic femoral shaft fractures comparing fixation techniques using cement.

To determine the most stable mode of internal fixation for the pathologic femoral shaft fracture with extensive cortical destruction, 2 fixation techniques incorporating methylmethacrylate were compared. Osteotomies through standardized cortical defects were created in intact embalmed femora to simulate a standard pathologic fracture. Fixation obtained with either intramedullary Schneider rods or 28-hold ASIF plates, both using bone cement, was compared in torsion and bending. In torsion, plate-fixed femora failed at a mean load of 71.2 newton-meters compared to 26.8 newton-meters for the Schneider rod counterparts. In bending, plate-fixed bones at a mean load of 8133.9 newtons compared to 1921.4 newtons for rod-fixed femora. Fixation with double plates and methylmethacrylate was clearly more stable and allowed for immediate pain-free ambulation.

Femoral Fractures↗
PubMedDate not supplied

Lymphangiomatosis and massive osteolysis of the cervical spine. A case report and review of the literature.

On the basis of clinical, radiographic, and pathologic evidence, massive osteolysis can be divided into two forms: Gorham's disease and angiomatosis. The present case is the first report of massive osteolysis of the lymphangiomatosis type involving the cervical spine but without visceral involvement. Originally, plain lymphangiomatosis was diagnosed, but the diagnosis was changed to massive osteolysis. Only one other case of lymphangiomatosis with cervical involvement was found, but in that case the viscera were also involved. Both cases exemplify a prolonged progressive pattern, recalcitrant to treatment and with a devastating outcome. Diagnosis by biopsy is difficult, and incremental radiation therapy early in the disease process should be considered.

Bone Resorption↗