The Dowling Club 1983-1984.
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Dermatology↗
Biomedical subjects
R C Staughton
Publications and source records attributed to R C Staughton.
Papuloerythroderma--a further case with the 'deck chair sign'.
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Abdomen↗
Hairy cell leukemia and pyoderma gangrenosum.
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Biopsy↗
Skin disease in homosexual patients with acquired immune deficiency syndrome (AIDS) and lesser forms of human T cell leukaemia virus (HTLV III) disease.
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Acquired Immunodeficiency Syndrome↗
Disseminated herpes simplex type 2 infection--a potentially lethal disease.
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Acyclovir↗
Dermatological aspects of the use of Cyclosporin A for prophylaxis of graft-versus-host disease.
Oral Cyclosporin A (CyA) was given for the prophylaxis of graft-versus-host disease (GVHD) to sixty-seven patients receiving a bone marrow transplant, and was found to be extremely effective in reducing the severity of acute GVHD. Side-effects of CyA included hypertrichosis, gum hypertrophy, and a rare but serious 'capillary leak' syndrome.
Adult↗
Toxic pustuloderma--a new entity?
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Adult↗
Oropharyngeal and laryngeal lesions in lipoid proteinosis.
This is a case report of a 25-year-old man, with severe lipoid proteinosis of the oropharynx and larynx, who underwent microlaryngeal surgery. The condition is discussed with particular reference to the surgical management of the laryngeal lesions.
Adult↗
Lipoid proteinosis: variations in the histochemical characteristics.
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Adult↗
Differential loss of T lymphocyte markers in advanced cutaneous T cell lymphoma.
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Antibodies, Monoclonal↗
Razoxane regimen for the treatment of psoriasis.
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Adult↗
Razoxane regimen for the treatment of psoriasis.
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Adult↗
Malignant histiocytosis presenting with skin ulceration.
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Head and Neck Neoplasms↗
Perineal suppurative hidradenitis.
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Anaerobiosis↗
Streptococcus milleri causing treatable infection in perineal hidradenitis suppurativa.
Streptococcus milleri was isolated from the active lesions of three patients with perineal hidradenitis suppurativa. In each patient, elimination of this organism by appropriate antibiotic therapy was accompanied by marked clinical improvement.
Adult↗
Thymosin-inducible 'null' cells in atopic eczema.
Thirty children with atopic eczema were compared with an equal number of age-matched healthy children. The mean peripheral blood T-lymphocyte level was lower in the eczema group (mean 1,197/mm2 as against 1,702/mm3; P = 0 . 003). This difference was abolished in vitro by thymosin, a thymic hormone extract. Positive correlations were found between eczema severity and: eosinophilia; hyperimmunoglobulinaemia E; but not T lymphopaenia. Thymosin-inducible T-cell (Ti) counts correlated with plasma IgE levels, suggesting that these Ti cells may be immature suppressor T cells. If this T-cell deficiency represents inadequate suppression of IgE responses, then a trial of treatment with thymosin appears to be warranted.
Adolescent↗