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Biomedical subjects

R C Sanders

Publications and source records attributed to R C Sanders.

167 records · Page 10Linked to original sources
PubMedDate not supplied

Gastric leiomyosarcoma: CT observations.

The abdominal CT examinations of seven patients with gastric leiomyosarcoma (GLMS), proven by surgical or endoscopic biopsy or both in five patients and percutaneous aspiration biopsy in two, are reviewed. In the six patients studied prior to therapy, CT demonstrated that each of the primary gastric tumors was spherical or ellipsoidal, large (mean diameter 15 cm), and predominantly exogastric in location. Additional CT features of the primary tumor included necrosis in all six masses, a distinct gastric mural attachment in four, bubbles of gas or an air-fluid level or both in three, and mucosal ulceration in two. Direct tumor invasion of nearby organs was suggested by CT in four of the six patients, the spleen and pancreas representing the most frequent sites. Intraperitoneal spread of tumor was present in two patients; necrotic liver metastases accompanied three of the six primary tumors and were found in an additional patient examined 4 years after gastric resection. By accurately reflecting the biological behavior of GLMS, CT is an ideal imaging modality for studying this unusual neoplasm. Differential diagnosis and specificity of the CT findings are discussed.

Adult↗
PubMedDate not supplied

Prenatal diagnosis of cystic adenomatoid malformation of the lung.

Cystic adenomatoid malformation of the lung (CAM) is an uncommon malformation in which normal tissue is replaced by cysts of various sizes. This malformation may be diagnosed prenatally with ultrasound by visualization of cystic masses in the fetal chest, which may occur in association with fetal hydrops. Three cases of fetal hydrops secondary to cystic adenomatoid malformation of the lung are described; in one case cystic lesions in the chest were clearly demonstrated.

Adult↗
PubMedDate not supplied

Ventriculitis in the neonate: recognition by sonography.

In the neonate, ventriculitis and inflammatory infiltration of the choroid plexus usually accompany meningitis. Intracranial sonograms were reviewed from six infants referred for evaluation because of clinically suspected or confirmed ventriculitis. Findings included ventricular dilatation with irregularity of the ventricular margins and increased periventricular echogenicity. The choroid plexus margins also appeared poorly defined with loss of the normally smooth contour. Echogenic material was seen within the lateral ventricles, and intraventricular septa formation resulted in ventricular compartmentalization. Parenchymal changes included periventricular cavitation and a diffuse increase in cortical echogenicity. The ventricular pathology was more apparent on sonograms than on computed tomographic scans obtained at comparable times. In particular, sonography better demonstrated the ventricular compartmentalization from intraventricular septum formation. Identification of such partial ventricular isolation is especially important when treatment involves intraventricular shunt placement or the administration of intraventricular antibiotics. This experience suggests sonography should be the initial imaging method for evaluating ventriculitis and its complications in the newborn.

Bacterial Infections↗
PubMedDate not supplied

Dandy-Walker syndrome: recognition by sonography.

The sonographic appearance of the Dandy-Walker malformation is not well known. Experience with sonography in the recognition of the Dandy-Walker syndrome in four neonates is presented. Three cases were discovered serendipitously: one during obstetric evaluation for uncertain gestational age and two in asymptomatic neonates. The typical sonographic features are a triangular posterior fossa cyst, a dilated aqueduct of Sylvius in communication with the cyst, elevation and hypoplasia of the cerebellum, and variable dilatation of the third and lateral ventricles. Sonography is often the first diagnostic procedure performed on these patients and can be very useful in recognizing the anomaly.

Dandy-Walker Syndrome↗