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Biomedical subjects

R C Miller

Publications and source records attributed to R C Miller.

At least 325 records · Page 18Linked to original sources
PubMed1973

Replication of T4 DNA in Escherichia coli treated with toluene.

Deoxyribonucleoside triphosphates are incorporated into T4 DNA in infected cells treated with toluene. Under the proper conditions the incorporation is controlled by the known T4 DNA polymerase and proceeds by a semiconservative mechanism. Both strands of the phage DNA are replicated into a high molecular weight progeny molecule. The replication system is accessible to extracellular pancreatic DNase added to the reaction mixture. At early times after infection a second replication system, not under control of the gene 43 polymerase, has been detected which synthesizes T4 DNA in toluenized cells.

Adenosine Triphosphate↗
PubMed1972

Association of replicative T4 deoxyribonucleic acid and bacterial membranes.

Experiments utilizing CsCl density gradient analysis and radioactive labels specific for bacteriophage T4 deoxyribonucleic acid (DNA) and membranes have shown that replicative T4 DNA is associated with host membranes. The association is inhibited by chloramphenicol and takes place just prior to semi-conservative replication of the phage DNA.

Bacterial Proteins↗