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Biomedical subjects

R C Harrison

Publications and source records attributed to R C Harrison.

At least 37 records · Page 2Linked to original sources
PubMed1971

Effect of cigarette smoking on human gastric secretory responses.

The effect of smoking three cigarettes over a one-hour period on the pentagastrinstimulated submaximal plateau of acid and pepsin secretion was observed in 12 healthy human volunteers comprising men and women and smokers and non-smokers. No significant overall change in secretion was observed. In one subject, however, acid secretion was significantly inhibited (p < 0.01) and in one individual significant late stimulation (p < 0.01) of both acid and pepsin was observed.

Adult↗
PubMed1970

The selective nerve stain leucomethylene blue as an intraoperative aid to achieving complete vagotomy.

The recently reported vagal nerve stain leucomethylene blue was assessed in 20 patients as an intraoperative aid to attaining complete vagotomy. Of 101 stained specimens removed at surgery, only 30 (30%) contained nerve tissue. Four of 17 postoperative insulin tests were positive by Hollander's criteria. The dye technique was found to be an unreliable method of ensuring complete vagotomy at the time of surgery.

Esophagus↗
PubMed1967

Surgical timing in biliary tract disease.

Based on 991 cases of biliary tract disease managed in a recent four-year period, the authors contrast an elective operative mortality rate of 0.6% against 4.4% for acute cholecystitis. Because in 21 of 28 patients with acute cholecystitis symptoms and signs subsided within 48 hours of conservative management in hospital, they recommend a two-day trial of conservative management for patients with acute cholecystitis and operation only for those who are not definitely improving under optimal conditions. The incidence and expected mortality from acute cholecystitis increased with age. Where possible, elective operation should be done when stones are first diagnosed because in patients over 65 years of age the rate of complications was four times and the mortality rate three times that in patients under 65. The incidence of cancer in cholelithiasis was sufficiently high that it is a significant factor in the consideration of prophylactic cholecystectomy. Patients with ruptured gall-bladders can present a trap for the unwary diagnostician; they should have minimal emergency surgery.

Aged↗