Search PubMed⌕ Search

Biomedical subjects

R C Fox

Publications and source records attributed to R C Fox.

At least 19 recordsLinked to original sources

Caregiver and elder experiences of Cambodian, Vietnamese, Soviet Jewish, and Ukrainian refugees.

Our purpose was to describe and compare Cambodian, Vietnamese, Soviet Jewish, and Ukrainian refugee caregivers and elders on life experiences, health status, and knowledge of available services. Detailed interviews were conducted with 105 female caregivers and 52 elders. Similar patterns emerged across all groups with regard to filial obligation, minimal knowledge of services, impact of immigration, and retention of cultural ties. Findings confirmed the special health and social service needs of refugee families in transition.

Aged↗

Time to heal medical education?

In Time to Heal: American Medical Education from the Turn of the Century to the Era of Managed Care, Kenneth Ludmerer presents a penetrating narrative and analytic account of the daunting economic, organizational, social, and value problems facing medical education that are threatening its excellence and its sense of purpose. The new conditions have the potential not only to seriously undermine the scientific and clinical quality and vibrancy of the education that medical students and housestaff receive, but also to subvert the development of core elements of a "Samaritan" concern for the care, the suffering, and the well-being of patients and of dedication to the public good. American medical schools have a long tradition of trying to improve medical education through periodic curriculum reforms. Since the famous and influential Flexner report in 1910, at least 24 other major reports advocating such reform have been issued, and they have been strikingly similar in their prescriptions. The resulting modifications have, however, been "reform without change" because of medical educators' failure to address the basic social, organizational, and financial problems with which medical schools have been progressively confronted. Ludmerer considers that today's problems, however formidable they may be, are not as profound as those that faced medical educators a century ago--and that there is time and opportunity for visionaries and leaders to act. This may be true but only if they can properly diagnose the present problems of medical education, amply understand their roots, identify effective means to remedy them, and galvanize medical educators to make the systemic, institutional changes, locally and nationally, that are called for.

Academic Medical Centers↗

Perish and publish: non-heart-beating organ donation and unduly iterative ethical review.

In the expanding repertoire of practices designed to increase the supply of organs for transplantation, non-heart-beating cadaver organ donation has generated an ongoing debate in the literature. The continuing stream of articles is disquieting in part because it documents a troubling "trial-and-error ethics" approach to the formulation of organ procurement policy, and because it raises serious questions about the reasons that the development of this policy is being mediated by published communication. In the light of concerns about the implicit support and credibility that professional publications give to organ procurement policies, restraint in publishing articles about non-heart-beating organ donation as well as in devising such policies is strongly advocated.

Cadaver↗

Noninvasive mechanical ventilation via face mask in patients with acute respiratory failure who refused endotracheal intubation.

OBJECTIVE: To evaluate the response to noninvasive ventilation in a group of terminally ill patients with acute respiratory failure who refused endotracheal intubation. DESIGN: Case series. SETTING: Medical intensive care units (ICUs) in a university health science center. PATIENTS: Eleven patients, nine with hypercapnic and two with hypoxemic acute respiratory failure. Mean age of patients was 64 yrs. INTERVENTION: Mechanical ventilation was delivered via a face mask. The initial ventilatory setting was continuous positive airway pressure mode, with pressure-support ventilation of 10 to 20 cm H2O, titrated to achieve a respiratory rate of < 25 breaths/min and a tidal volume of 5 to 7 mL/kg. Ventilatory settings were adjusted based on results of arterial blood gases. Mean duration of mechanical ventilation was 44 hrs. MEASUREMENTS AND MAIN RESULTS: Mechanical ventilation via face mask was effective in correcting gas exchange abnormalities in seven of 11 patients, all of whom survived and were discharged from the ICU. Four patients with hypercapnic acute respiratory failure died. Mechanical ventilation via face mask was effective in improving respiratory acidosis in three patients and had no effect in one patient. Two of the four patients could not be weaned from mechanical ventilation and opted for discontinuation of this method. Removal of the ventilator while retaining the mask for oxygen supplementation was a nontraumatic experience to the patient and family. Even when respiratory failure did not resolve, mechanical ventilation via face mask was effective in lessening dyspnea and allowed the patient to maintain autonomy and continuous verbal communication. CONCLUSIONS: We conclude that mechanical ventilation via face mask offers an effective, comfortable, and dignified method of supporting patients with end-stage disease and acute respiratory failure.

Acute Disease↗

Post-Jurassic mammal-like reptile from the Palaeocene.

Mammal-like reptiles of the order Therapsida document the emergence of mammals from more primitive synapsids and are of unique zoological and palaeontological interest on that account. Therapsids, first appearing in the Early Permian, were thought to become extinct in the Middle Jurassic, soon after the Late Triassic origin of mammals. Here, however, we report the discovery of a therapsid from the late Palaeocene, 100 million years younger than the youngest previous occurrence of the order. This discovery nearly doubles the stratigraphic range of therapsids and furnishes their first record from the Cenozoic. The documenting fossils, an incomplete dentary containing three teeth, and four isolated teeth from other, conspecific individuals (Fig. 1), are from the Paskapoo Formation, at Cochrane, Alberta, Canada, from beds yielding a diverse mammalian fauna of early Tiffanian age. These specimens are catalogued in the collections of the University of Alberta Laboratory for Vertebrate Paleontology (UALVP) and provide the basis for a new taxon, as named and described below: (see text)

Animals↗

Noninvasive face mask mechanical ventilation in patients with acute hypercapnic respiratory failure.

Mechanically assisted intermittent positive-pressure ventilation effectively provides ventilatory support in patients with respiratory failure but it requires placing an artificial airway. We have previously reported our successful experience delivering mechanical ventilation via a face mask (FMMV) rather than with an endotracheal tube in a pilot study of patients with acute respiratory failure. The present investigation evaluated an additional 18 patients with hypercapnic respiratory failure to determine the efficacy of FMMV in a more homogeneous group and to determine factors predicting its success. FMMV was successful in avoiding intubation in 13 of the 18 patients. A significant initial improvement in PCO2 (greater than 16 percent decrease) and in pH (from less than 7.30 to greater than 7.30) predicted success. The five patients who failed on FMMV required endotracheal intubation because of inability to improve gas exchange (three patients), apnea due to sedatives (one patient), and management of secretions (one patient). FMMV was generally well accepted with only two patients withdrawn because of intolerance of the mask. The mean duration of FMMV was 25 h. Complications were seen in only two patients (11 percent): aspiration (one patient) and mild skin necrosis (one patient). Seven patients entered the study by meeting entrance criteria after an unsuccessful extubation attempt and therefore received both forms of mechanical ventilation. All but one patient avoided reintubation, and the face mask proved to be as effective as the endotracheal tube as a conduit for delivering the mechanical tidal volume and improving gas exchange. Our findings indicate that FMMV is a viable option for short-term (one to four days) ventilatory support of patients with hypercapnic respiratory failure and insufficiency.

Acidosis, Respiratory↗

Medical uncertainty and the autopsy: occult benefits for students.

The autopsy has been of great importance in educating students regarding medical uncertainty. The marked decline in the use of the autopsy in medical education and continuing education has contributed significantly to the current discomfort among physicians regarding medical uncertainty and medical errors, which, in turn, has furthered the decline of the autopsy. Inordinate guilt, denial, and other defensive behaviors that many physicians marshall in response to uncertainty and error prevent these individuals from learning from their mistakes. The autopsy experience during medical school, properly utilized, helps students to confront fallibility and sets the stage for later successful management of uncertainty and error.

Autopsy↗

The culture of caring: AIDS and the nursing profession.

Caring for persons with AIDS calls upon a range of physical, psychological, social, and spiritual interventions that, in the absence of a cure, can make a palpable difference for patients. The "culture of caring" that nurses bring to bear on the epidemic is shaped by their education and socialization, and by shared background characteristics. The nursing profession has been among the leaders in organizing AIDS care; such care entails stress for individuals at a time when the profession and the health care system are facing a generalized crisis, but nurses have testified to the redeeming significance they find in performing their work. It remains to be seen whether the contribution nurses and their ethos of caring have made will endure to influence the relative status of this profession.

Acquired Immunodeficiency Syndrome↗