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Biomedical subjects

R C Bowen

Publications and source records attributed to R C Bowen.

33 records · Page 2Linked to original sources
PubMed1987

A case of atypical psychosis associated with alexithymia and a left fronto-temporal lesion: possible correlations.

The case history is presented of a man with an atypical psychosis and classical clinical features of alexithymia. On his last admission, the patient presented with starvation and hypernatremic coma. A CT scan, which was done because of the coma, revealed a large left fronto-temporal arachnoid cyst. The significance of this finding is reviewed in the light of previously suggested organic bases for alexithymia and related syndromes. Although the symptom of alexithymia is present, the patient's other symptoms do not fit readily into existing diagnostic categories and the resulting diagnostic dilemma is discussed.

Adult↗
PubMed1984

Types of depression in alcoholic patients.

Standardized clinical interviews of 48 alcoholic patients consecutively admitted to an alcoholism treatment program revealed that 22 (46%) had suffered major depressive episodes. However, only two had the typical depressed affect at the time of the interview. Cyclic mood swings, panic attacks and hypomania were common, indicating that this was a heterogeneous group of depressed patients. The alcoholism tended to precede the onset of depression, which was then followed by the seeking of help, but the whole sequence developed over a few years, when the patients were in their early 20s. The depressed patients had more psychiatric, marital and legal difficulties than the nondepressed patients. There is a need for better definitions of affective disorders in alcoholic patients.

Adult↗
PubMed1983

Differential diagnosis of anxiety disorders.

The literature comparing panic disorder with natural fear, hypoglycemia, hyperthyroidism, pheochromocytoma, the hyperventilation syndrome, the mitral valve prolapse syndrome and partial complex seizures is briefly reviewed. Some features of each of these syndromes may clinically resemble panic disorder. It is concluded that: a) patients with panic disorder should be medically evaluated. b) the diagnosis of panic disorder should be based on a broad system, rather than on symptoms alone. c) diagnostic systems should include a category for "organic anxiety syndromes".

Adrenal Gland Neoplasms↗
PubMed1983

A study of the catabolism of trace amines in mentally disordered individuals with particular reference to agoraphobic patients with panic attacks.

Platelet MAO activity toward several trace amine substrates and the plasma levels of some trace acids have been investigated. Compared to controls, the agoraphobic patients were found to have significantly increased MAO activity. The substrate specificity in some of the patients appeared to be altered. The plasma levels of p-HPA and m-HPA were significantly lower than those of the control groups.

Adult↗
PubMed1983

Platelet monoamine oxidase activity and trace acid levels in plasma of agoraphobic patients.

Platelet monoamine oxidase activity and plasma trace acid levels in 29 patients classified as agoraphobics was estimated. MAO activity towards p-tyramine and beta-phenylethylamine was found to be significantly higher in agoraphobics than in non-agoraphobic depressed patients and healthy controls. In addition plasma p-hydroxyphenylacetic acid levels were low in both agoraphobic and depressed patient groups. All patients were also assessed by Spielberger State Anxiety and the short form of the Beck Depression Inventory scales. No significant correlations could be found between platelet MAO activity or plasma trace acid levels and the psychological scores.

Adult↗
PubMed1982

Agoraphobia.

Explore the source record for details and available documents.

Agoraphobia↗
PubMed1979

The relationship between agoraphobia and primary affective disorders.

Detailed clinical records were kept on a series of 55 agoraphobic patients who presented to a general hospital psychiatric practice over a 3 year period. A review of the records revealed that 91% of these patients were diagnosed as suffering from a unipolar or bipolar primary affective disorder. The anxiety and phobic symptoms tended to mask the presence of the affective disorder. This observation is consistent with most of the published data on the agoraphobic syndrome. It could also explain the inconsistent effects of treatment of agoraphobia compared with simple phobias. The possible biological and psychological connections between primary affective disorders and the agoraphobic syndrome are discussed.

Adjustment Disorders↗
PubMed1977

Physical and psychological complications after intestinal bypass for obesity.

Cognitive changes, depression, arthralgia and dermatitis developed in a 33-year-old woman 5 years after a jejunoileal shunt for massive obesity, The dermatitis and low serum carotene and vitamin C values suggested vitamin deficiencies, The serum magnesium concentration also was low. Vitamin and mineral replacement led to amelioration of the physical and psychological symptoms; the improvement has been maintained at 18-month follow-up. The favourable changes were documented with the Wechsler Adult Intelligence Scale, the Minnesota Multiphasic Personality Inventory and test performance ratings. It is concluded that the surgical procedure caused vitamin and magnesium deficiencies and that these resulted in the patient's symptoms.

Adult↗
PubMedDate not supplied

The effect of diazepam on the recovery of endogenously depressed patients.

Forty endogenously depressed patients given standard antidepressants and/or electroconvulsive therapy in a general hospital psychiatric ward were assessed using the short form of the Beck Depression Inventory and the Hamilton Depression Rating Scale. The patients were then randomly assigned to two groups: Under double-blind conditions, one group received in addition 20 mg diazepam per day and the other, identical placebos. No additional benzodiazepines were prescribed during the study. Standard therapy with tricyclic antidepressants or electric shock was determined by the patients' own psychiatrists. The assessments were repeated after ten days of diazepam or placebo treatment. Fourteen patients (seven in each group) also completed the Buss-Durkee Hostility Inventory. Results of the Beck Depression Inventory indicated that the addition of diazepam retarded the improvement of the patients receiving only tricyclic antidepressants but had no effect on the recovery of patients receiving electroconvulsive therapy.

Adolescent↗
PubMedDate not supplied

A controlled trial of cognitive behavioral treatment of panic in alcoholic inpatients with comorbid panic disorder.

Patients entering a 4-week inpatient alcoholism treatment program were screened for anxiety symptoms. Those with panic disorder with or without agoraphobia were randomly assigned to two groups. The treatment group received 12 hours of cognitive-behavioral treatment (CBT) for panic disorder in addition to the regular alcoholism treatment program: the control group received the regular program. Dropouts from the treatment group were also followed. Problem drinking and anxiety symptoms were measured at the start of the study, and at 3, 6, and 12 months posttreatment. Abstinence from drinking, and anxiety and mood symptoms improved after treatment in all of the groups; there were few differences in outcome between the groups. We concluded that this particular intervention had not been more effective than the regular alcohol treatment program in reducing problem drinking in those with panic disorder.

Adult↗
PubMedDate not supplied

Alcoholism, anxiety disorders, and agoraphobia.

A group of 48 inpatient alcoholics were studied using the Schedule for Affective Disorders and Schizophrenia--Life-time Version (SADS-L) and the Brief Standard Self-rating for Phobic Patients. Approximately one-quarter of the patients were diagnosed as suffering from agoraphobia and social and mixed phobias. Approximately 44% were diagnosed as suffering from anxiety disorders and 46% had suffered from an episode of major depression. Data from the self-rating questionnaire were consistent with the diagnostic data. The alcoholics with phobias had experienced more severe dysphoric feelings than nonphobic alcoholics with other psychiatric disorders.

Adult↗