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Biomedical subjects

R C Bishop

Publications and source records attributed to R C Bishop.

13 recordsLinked to original sources
PubMed1996

Anterior cervical interbody fusion using autogeneic and allogeneic bone graft substrate: a prospective comparative analysis.

The authors conducted a prospective study of 132 patients requiring interbody fusion without instrumentation following anterior cervical discectomy to compare the efficacy of tricortical iliac crest allograft versus autograft fusion substrates. The objectives of the study were to assess the potential differences in interspace collapse, angulation, maintenance of cervical alignment and lordosis, and clinical and radiographic fusion success rates between the two fusion substrates. The impact of habitual cigarette smoking on fusion rates was also examined. Autograft tricortical iliac crest bone was found to be superior to allograft bone as an interbody fusion substrate after both single- and multiple-level anterior cervical decompression procedures with respect to maintenance of cervical interspace height, interspace angulation, and radiographic and clinical fusion success rates. Cigarette consumption had a significant adverse effect on successful anterior cervical interbody fusion for both autograft and allograft substrate, an effect that was most pronounced among smokers treated with allograft bone (p = 0.004).

Adult↗
PubMed1987

Immunoglobulin therapy for autoimmune thrombocytopenia purpura during pregnancy. A report of two cases.

High-dose, intravenous immunoglobulin therapy may be effective in elevating low platelet counts in nonpregnant patients with autoimmune thrombocytopenia purpura (ATP). We used immunoglobulin successfully on two pregnant women with ATP who had been refractory to high-dose corticosteroid therapy. The 5-day infusions were started at 12 and 29 weeks' gestation, and the subsequent uncomplicated vaginal deliveries occurred after the shortest reported interval (8 days) and longest (28 weeks) following a single immunoglobulin infusion. A splenectomy was avoided, and no adverse maternal or neonatal effects were apparent.

Adult↗
PubMed1981

Response factors in the choice of reference ear in ABLB.

Response patterns and the limits of loudness judgement accuracy were explored in a clinical presentation of the alternate binaural loudness balance (ABLB) procedure, and compared across the two methodological alternatives of using the better or poorer ear as reference ear. It was found: 1) that in the range of judgement uncertainty, responses were strongly influenced by stimulus presentation order; 2) that the magnitude of the range of uncertainty was similar across both methodologies. A suggested clinical procedure which controls for these effects is presented as an Appendix.

Acoustic Stimulation↗
PubMed1980

Disorders of iron metabolism.

Although iron in minute amounts is necessary for the metabolism of most cells, it produces damage if present in excess. Clinical tools for the evaluation of iron stores include serum iron concentration, transferrin saturation, deferoxamine test, Prussian blue stains of liver and marrow, and serum ferritin concentration. Serum ferritin concentration is an excellent screening test for iron deficiency or excessive iron stores. If excessive iron stores is diagnosed, the iron should be removed with phlebotomies or chelation therapy.

Absorption↗