[Cancers of the pancreas. A plea for excision].
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Biomedical subjects
Publications and source records attributed to R Bricot.
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The results of 73 consecutive curative resections for adenocarcinoma of the gastric antrum (37 distal subtotal gastrectomies and 36 electively extended total gastrectomies) are presented. The location and size of the tumour and the degree of lymph node involvement were similar in both groups (excluding superficial carcinomas), but the patients with subtotal gastrectomy were significantly older than the others (mean age : 70.5 and 59 years respectively). The operative mortality rate was 13.6% in each group, but the post-operative hospital stay was longer for total gastrectomy patients. The five-year survival rate overall (including operative deaths) was 44.3%. There was no difference in survival rate between the two types of operation (49.7% for subtotal, and 45.6% for total gastrectomy, operative deaths excluded). Survival was related to the degree of parietal spread and nodal involvement. These results are in favour of subtotal gastrectomy for antral adenocarcinoma.
The authors report the case of a left paraduodenal hernia which involved almost the entire small intestine in a 15 year old girl who presented with recurrence episodes of acute abdominal pain associated with König's syndrome. Radiologic examination (plain film of the abdomen and upper GI series with small bowel follow-through) was suspicious, but did not establish the diagnosis due to unfamiliarity with the radiologic appearance of the condition. The roentgenograms are shown as well as the intraoperative findings. Anatomic, pathophysiologic, clinical, and radiologic characteristics are reviewed.
It appears that there are a certain number of complications in the digestive tract that still occur in spite of improvements in techniques of irradiation therapy. They may only appear a few months or even a few years after the treatment, and sometimes they only appear when the initial growth is considered to have been cured. The clinical picture is dominated by the appearance of fistulae, of adhesions and of stenoses which give rise to sub-acute or sometimes acute obstructions. From the anatomical point of view all elements of the digestive tube are affected with a predominance of the fibro-hyaline elements of the muscles and the arteries. The possibilities for surgical treatment are limited. Excision with anastomosis would seem to be more risky than diversion. We have had to operate on ten of our eleven patients, of whom six died and only one of these directly because of recurrence of the initial growth. Only prevention can lessen the mortality of these severe complications.
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Endometriosis involving the digestive tract accounts for 1% of all cases of the disease. There is a marked predominance in the recto-sigmoid and terminal ileal loops. Symptomatology is dominated by disturbances in intestinal transit, sub-occlusion or acute obstruction, pain worsening at the time of menstruation and by a haemorrhagic rectal discharge again accompanying menstruation. Apart from classical aetiopathogenic theories such as grafting onto the digestive tract by tubal, lymph vessel or venous propagation, it would appear that prostaglandins and in particular a change in the (formula; see text) ratio may play a large role. Operative resection of localised stenosis combined with oophorectomy, if the latter is possible in view of the patient's age, or prolonged medical treatment with progestational agents or even better Danazol results in cure and avoids recurrences.
The results of primary perineal closure after rectal resection for cancer are reported, about a series of 105 patients male and female; to whom this technique was systematically applied. The healing of the wound was primarily obtained in 77.2% of the cases (82.3% in males, 72.2% in females). 86% of the patients left the hospital completely healed within 30 post operative days. The authors stress the influence of the environment on the result and also discuss the practical conditions of the primary suture: hemostasis, fecal contamination, peritonisation, enlarging followed with ablation of the genital tract in women.
Anastomotic stricture is an unusual complication of the colo-rectal surgery ; this can be very difficult to manage, particularly in low anastomosis. About one case successfully treated, the authors suggest an original non operative treatment : a resection with simultaneous anastomosis only performed through a transanal approach, with upper coloscopic control.
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The authors are reporting 10 cases of operated cystohepatic ducts. In each case there is a unic duct, leading five times in the gallbladder, and once in the cystic duct. In 8 cases this abnormality was shown intraoperatively. In 2 cases the diagnosis was only given during the surgical procedure, when a fistulography was performed. In one case it was necessary to reoperate. In four cases during the cholecystectomy we had to ligate the cystohepatic duct. In order to argue these cases, a literature review was done: 42 cases were found. The ligation of a cystohepatic duct is in most cases without consequences. the different ways of restoration are studied when large ducts are found. The best treatment of such an abnormality seems to be an anterograde cholecystectomy associated to a systematic drainage of the gallbladder region.
The authors report a case of chest injury causing rupture of the right ventricle and diaphragm, discovered during laparotomy for haemoperitoneum. This type of injury to the heart has rarely been cited in the literature since survival rates are low and the diagnosis often overlooked.
The authors give 9 case histories of endometriosis localised to the abdominal wall : 3 of them in the umbilicus, 3 in laparotomy incisions (2 of those were Caesareans), 2 of them in the round ligaments at the external opening of the inguinal canal and 1 of them in the right rectus muscle sheath in the abdomen. The functional symptomatology is rhythmical according to menstruation; it is associated with a burning type of pain, a tumour and blood loss. Over and above the theories of aetiology that are now classical, namely tubal retrograde spill, and lymphatic or venous spread, it would seem that prostaglandins and in particular the ratio of P.G.E. divided by P.D.F2 alpha can play a big role. Although Danazol is an effective treatment for endometriosis, the treatment of choice is, in these lesions that are superficial in localisation and easily accessible, to cut them out surgically. This makes it possible on the one hand to look for other intra-abdominal lesions and also on the other hand to confirm the anatomy and pathology (this was done in 7 out of 9 of our cases).
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The present study reports the results of several methods used to perform abdominal resection (with anastomosis fastened by means of sutures and clip-gun) abdomino-transanal method designed to preserve sphincter function (Babcok,, Toupet, Duhamel), anterior abdomino-perineal resection and tumorectomy. The indications of these different surgical techniques are discussed and the authors point out the necessity to do not give up the carcinologic needs to the sphincteral preservation.
The authors report two cases of hepatic artery's ligature in patients suffering from pan-hepatic metastases in carcinoid tumor of the bowels. They have come to believe that the hepatic devascularization (by removing the carcinoid syndrome and associated hepatalgia) offers a more comfortable chance of survival to the patient, giving him often the illusion that he is cured.
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The authors report a case of blunt traumatic rupture of the right ventricle, diagnosed during a laparotomy. Similar cases were seldom met: too short a time of spontaneous survival, and difficult challenging diagnosis explain it.
Analysis of the surgical criteria for reintervention in Abdominal Surgery led to the accentuation of a certain number of pictures of occlusion, general infectious syndromes, postoperative peritonitis, gastro-intestinal fistula and hemorrhagic syndrome. In all cases, the clinical examination can be misleading in particular in the case of peritonitis, and the history and non-surgical criteria must be strongly borne in mind.