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Biomedical subjects

R Bjerknes

Publications and source records attributed to R Bjerknes.

92 records · Page 6Linked to original sources

The association between nutritional conditions during World War II and childhood anthropometric variables in the Nordic countries.

BACKGROUND: The purpose of the study was to examine the height and weight in Nordic children during the years around World War II (WWII), and compare them with the nutritional situation during the same period. METHODS: Information on food consumption and energy intake were obtained from the literature. Anthropometric data were collected from the Nordic capitals and cover the period from 1930 to 1960 for ages 7-13 years. RESULTS: The greatest energy restriction took place in Norway (20%), followed by Finland (17%), while Sweden and Denmark had a restriction of 4-7% compared to pre-war levels. The most pronounced effect of WWII on height and weight is seen in Norwegian children, while some effect is observed for the youngest children in Finland. Little or no effect is seen in Sweden and Denmark. CONCLUSION: The Nordic children were affected by WWII in terms of a transient reduction in temporal trends in height and weight, and the magnitude of this decrease was associated with the severity of the energy restriction prevailing in the respective country during the war. These findings warrant further studies of the chronic diseases associated with height and weight for cohorts being in their growth periods during WWII.

Adolescent↗

Flow cytometry for the study of phagocyte functions.

Phagocytes play a key role in host defense, and cell defects are associated with increased susceptibility to infection. Flow cytometry offers rapid and reproducible measurements of single cells in suspension and, following staining with one or more fluorochromes, simultaneous examination of several cell functions. Subpopulations of cells can be identified and sorted for morphologic, biochemical, and functional examination, and specially adapted computer systems allow storage of data for subsequent detailed analysis. Several flow-cytometric assays for the study of phagocytes and their interactions with microorganisms have been developed. These assays facilitate the study of (1) phagocyte surface receptors and regulatory molecules; (2) membrane potential; (3) phagocytosis of microorganisms, including the discrimination between attachment to the phagocyte surface and actual internalization; (4) phagosomal pH; (5) degranulation and enzymatic activity; (6) intracellular calcium; (7) oxidative metabolism; (8) intracellular killing of microorganisms; (9) degradation of microorganisms; and (10) exocytosis. In addition, the influence of serum opsonins on phagocyte-microorganism interactions can be studied. Flow-cytometric techniques are applicable to both experimental and clinical work.

Cell Separation↗