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Biomedical subjects

R Betti

Publications and source records attributed to R Betti.

111 records · Page 7Linked to original sources

Sporadic generalized lentiginosis without systemic involvement.

A 42-year old Caucasian man with generalized, acquired lentiginosis and no other associated diseases is described. A brief discussion about the significance of the term lentiginoses, the problems of their classification and nomenclature is also presented. The presence at the histopathologic examination, of some junctional nests of melanocytes provides the basis for a discussion of the relationship of the case presented, as well as other lentiginoses, with melanocytic naevi.

Adult↗

Eruptive dermatofibromas and immunosuppression.

Multiple and eruptive dermatofibromas are, on the contrary, unusual. Often the patients who show this peculiar cutaneous pattern are referred for immunosuppressive therapy or they have an immunosuppressive disease. We report the case of a woman affected by mycosis fungoides, who developed, in 2 months, 14 dermatofibromas on her legs. The personal history of the patient revealed a previous immunosuppressive treatment with systemic corticosteroids for interstitial pneumonia. Different etiological hypothesis have been proposed to explain the eruptive presence of multiple dermatofibromas and the alteration of the immune response, but the real mechanism is still unclear. Dermatofibromas are benign tumours usually encountered in dermatology.

Diagnosis, Differential↗