Search PubMed⌕ Search

Biomedical subjects

R Bergamaschi

Publications and source records attributed to R Bergamaschi.

At least 163 records · Page 9Linked to original sources
PubMed1989

Synchronous carcinoma of the colon and rectum: prognostic and therapeutic implications.

In a series of 1,037 patients with colorectal carcinoma diagnosed at one hospital during a 9-year period, synchronous cancers of the colon and rectum occurred in 2 percent. Patient characteristics and presenting symptoms were similar in single and synchronous carcinomas. The frequency of patients with associated benign neoplasms was significantly higher than that in the parent series. An examination of the modified Dukes' classification stage of the lesion in each patient revealed a higher incidence of lymph node involvement and a greater frequency of mucinous adenocarcinoma in patients with synchronous carcinomas. The 5-year survival of patients with synchronous growths did not differ from that of patients with single lesions, even when classified by Dukes' stage. Preoperative diagnosis was difficult, being achieved in no more than 30 percent of patients. Because of the poor accuracy of barium studies, total colonoscopy is the method of choice for this evaluation. We adopted a conservative surgical policy backed by life-long follow-up.

Adenocarcinoma↗
PubMed1989

Multiple sclerosis: disability and mortality in a cohort of clinically diagnosed patients.

A sample of hospitalized MS patients was selected according to clinical and demographic criteria with the aim of establishing prognostic factors. The sample included 52 patients with first hospitalization from 1 January, 1975, to 31 December, 1976. At follow-up after 12 years a malignant course was observed in 33 patients (death in 13, severe disability in 20 patients). The malignant course was related to age at onset (greater than or equal to 35 years) and higher disability, progressive course and cerebellar symptoms at onset. One half of patients with a relapsing-remitting course entered into a progressive phase of the disease after a mean duration of 7.3 years.

Adolescent↗
PubMed1989

[Parotidectomy as prophylaxis in malignant melanoma of the fronto-temporal and eyelid skin].

Three patients presented with parotid masses which revealed, on frozen section, to be metastatic lesions from malignant melanoma. Their medical history confirmed that the removal of cutaneous lesions of the frontal, temporal or eyelid skin had been performed presumedly without histologic examination. Disease staging was assessed as p-T0N1M0. Parotidectomy was performed in all cases without complications, and DTIC was given in one case. One patient died six months after surgery for metastatic disease, another one died disease-free, the third is available for the follow-up. The Authors recommend parotidectomy for prophylaxis in malignant melanoma more than 0.75 mm in thickness which is within a few centimeters of the parotid gland area. Lymphoscintigram might be useful occasionally.

Adult↗
PubMed1989

Growth and sport.

In order to investigate sport's influence on growth during puberty, we examined 398 boys 10-16 yr old. 192 of these subjects had been playing football as a competitive sport, and 206 were considered as controls, having never practised sports regularly. Both groups were divided into prepubertal (with testicular volume less than or equal to 2.5 cc) and pubertal, with the latter further divided into the following chronological and bone age groups: 10-11.99, 12-13.99, 14-16 yr. In these subjects we evaluated auxological-anthropometric and biological maturity characteristics and endocrine parameters (cortisol, dehydroepiandrosterone sulphate, testosterone). No significant difference was found between prepubertal athletes and controls concerning anthropometric and biological maturation parameters, whereas testosterone basal levels were significantly lower (p less than 0.05) and DHEAS values were significantly higher (p less than 0.05). Pubertal football players were significantly taller than controls (particularly at 14-16 yr chronological age), with a greater biacromial diameter after 12 yr chronological and bone age and thinner skinfolds at 12-13.99 chronological and bone age. They were more advanced in all biological maturation parameters i.e. pubic hair, testicular volume and bone age, particularly those subjects playing football for the greatest number of years and training time. In pubertal football players the increase in DHEAS (p less than 0.05) already seen in prepubertals is also combined with a significant increase in testosterone (p less than 0.0001) and cortisol (p less than 0.05). Thus football players DHEAS is already higher during prepuberty and this increase chronologically precedes the advance in all the auxological-maturative parameters typical of our pubertal subjects.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMed1989

Papillary thyroid cancer with unusually aggressive behaviour. Case report.

A 22-year-old woman underwent thyroid lobectomy for papillary carcinoma (follicular variant). Local recurrences 4 and 7 months later, with vascular invasion and extrathyroid spread, required extensive surgery and radiotherapy. Ipsilateral lobectomy with near-total or total contralateral lobectomy is advocated for treatment of papillary thyroid cancer.

Adult↗
PubMed1987

A prospective study of current diagnostic procedures for assessment of hepatic metastases in colorectal cancers.

In a prospective study of 305 patients with colorectal cancers, we assessed the diagnostic value of ultrasonography and laboratory tests. In each case laparotomy was carried out and the presence of liver metastases was established in 47 patients. The results show that the laboratory tests alone are not sufficiently accurate to detect liver metastases. Additional accuracy can be obtained by the combined use of a single liver imaging test (echography) and selected laboratory tests (C.E.A., gamma GT, Alkaline Phosphatase).

Adult↗
PubMed1987

Multimodal evoked potentials in multiple sclerosis: a contribution to diagnosis and classification.

The adoption of multimodal evoked potential procedures for the diagnosis and classification of multiple sclerosis is recommended as capable of revealing subclinical lesions of the central nervous system. The CSF test is also helpful, though in a different way. We present the results obtained by VEP, BAEP, SEP-median and SEP-tibial examinations and by CSF analysis (OB+) in a group of 189 MS patients, of whom 103 were diagnosed as definite. 58 as probable and 28 as suspected MS cases according to McDonald and Halliday, criteria. EPs frequently displayed clinically silent lesions, enabling us to reclassify 14 of the 37 potentially reclassifiable subjects (37.8%). The CSF test (OB+) allowed the reclassification of 31 out of the 58 reclassifiable cases (53.4%). In the present report we discuss the usefulness of the two methods.

Adolescent↗
PubMed1986

Colorectal cancer in patients under 40 years of age.

In a review of 1037 patients with colorectal cancers, there were 32 patients below the age of 40 years (3 percent). Rectal bleeding and abdominal pain were the most common presenting symptoms. The average delay between the onset of symptoms and treatment was 6.5 months. An analysis of tumors according to Dukes' staging revealed no significant difference between young and elderly patients. The younger patients had a greater frequency of mucinous and poorly differentiated carcinoma. When compared by clinical staging, however, the young patient did as well or better than his older counterpart. Clinical staging was the most important prognostic factor, irrespective of age. No inherent difference was found in the virulence of the cancer in the young, and five-year survival rates were not significantly different in young and old patients (59 percent vs. 49 percent).

Adenocarcinoma↗
PubMed1986

Facilitating low colorectal anastomosis. Preliminary results.

Low anterior resection with a stapled anastomosis is the operation of choice for almost all rectal lesions in which the sphincter can be safely preserved. We have reported the results of a new technique using the EEA stapler. This method is easy and safe, it eliminates the use of a low pursestring suture, avoids spillage, and keeps contamination to a minimum. It also allows the joining of bowel segments of disparate sizes. The results of this technique used in 16 patients with colorectal anastomoses are encouraging.

Adenocarcinoma↗