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Biomedical subjects

R Baumann

Publications and source records attributed to R Baumann.

293 records · Page 17Linked to original sources

[Esophagogastroduodenal localizations of Crohn's disease are frequent].

The purpose of this study was to determine the endoscopic features, actual frequency and consequences of upper digestive involvement in Crohn's disease (CD). Between April 1973 and April 1985, one or several upper digestive tract endoscopies with biopsies were performed in 129 of 195 patients admitted for ileal and/or colorectal CD. Endoscopic lesions were small and superficial: aphtous and superficial ulcerations, or erythematous areas. The diagnosis of upper digestive involvement was probable in 36 of the 129 patients who underwent upper endoscopies (28 p. 100), certain (microscopic evidence of granuloma) in 21 patients (16 p. 100). Lesions were isolated or multifocal but their preferential sites were the antrum and proximal duodenum. Histologic study of biopsies showed that granuloma were as frequent in upper as in lower intestinal lesions of CD. A frequency of 20 p. 100 seems to us to be more correct than the 5 p. 100 usually admitted. In our experience, upper digestive involvement in CD could not be regarded as a pejorative prognostic factor. It was sometimes possible to identify colitis or a peptic ulcer disease as a lower or upper digestive manifestation of CD, respectively.

Adult↗

[Radiological double contrast examination in Crohn's colitis. A report about 115 cases (author's transl)].

The authors had examined by double contrast barium enema in 115 cases of Crohn's ileo-colitis. They described the radiological double contrast features. The "early lesions" are always surrounded by a healthy-looking mucosa. The advanced lesions are segmentary: shallow limited ulcers, shallow confluent ulcers, cobblestone pattern and nodular pattern. Several types of lesions may appear in the same patient. The distribution of the lesions is asymmetrical with skip areas and gradual size of the lesions. The parietal lesions are well demonstrated by double contrast, especially the sacculations. Our radiological findings are confirmed by endoscopical features and excised specimens in 100 cases. A double contrast barium enema is necessary to well described the lesions especially the "early lesions" which are important for differential diagnostic, with ulcerative colitis, for surgical treatment in evaluating the extend of the disease and possibly even for prognosis in this disease.

Adolescent↗

[Epiphysis-metaphysis bone ischemia in hemorrhagic rectocolitis and Crohn's disease].

Aseptic osteonecrosis is a rare extraintestinal manifestation in patients with inflammatory bowel disease; its true prevalence is not precisely known. Steroid treatment undoubtedly participates in the pathophysiology of avascular osteonecrosis, however, other factors like hypercoagulability may be involved. Two cases of bilateral osteonecrosis of the knees--the first occurring during the course of ulcerative colitis, the second in a patient presenting with Crohn's disease--are described. Specific location of the lesions and regression of symptoms, as well as the importance of magnetic resonance imaging for early recognition of osteonecrosis, are noteworthy.

Adult↗