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Biomedical subjects

R Bataille

Publications and source records attributed to R Bataille.

At least 253 records · Page 14Linked to original sources

[Cementomas].

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Adult↗

[The implantations].

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Anti-Bacterial Agents↗

Human natural killer cells suppress the proliferation of B cells.

We have investigated the suppressive effect of human natural killer (NK) cells on autologous B-cell proliferation. Removal of NK cells by anti-NK-cell monoclonal antibodies (CD16, Leu 11b; Leu 7) increased by 2-3-fold the proliferative response of purified B cells activated by anti-mu and B-cell growth factor (BCGF). The inhibitory effect of NK cells was observed using recombinant IL-2 or semi-purified BCGF-I as sources of BCGF. Moreover NK cells, highly purified by centrifugation on a Percoll discontinuous density gradient, suppressed the proliferative response of purified autologous B cells activated by anti-mu and BCGF. These results show a suppressive effect of human NK cells on B-cell proliferation in vitro.

Antibodies, Monoclonal↗