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Biomedical subjects

R Bastin

Publications and source records attributed to R Bastin.

At least 55 records · Page 3Linked to original sources
PubMed1981

[Asiatic dengue in France: 9 cases, of which one of the thrombopenic type (author's transl)].

Asiatic dengue was detected in nine tourists. In eight patients it was of the classical benign type, the ninth case being associated with severe thrombopenia (4 000/mm3), but without signs of shock. A brief summary is given of the physiopathology of the hemorrhagic forms of the disease: acquired sensitivity from a primary attack and reinfection with a heterologous virus; selection of virulent strains by an atypical vector; genetic recombination producing a strongly pathogenic virus.

Adult↗
PubMed1980

[Indigenous Legionnaires' disease. Importance of clinical symptoms (author's transl)].

The first case of legionnaires' disease indigenous to France is reported. Since rapid bacteriological and/or serological diagnostic procedures are lacking, the disease should be suspected clinically in patients presenting with febrile pneumonia typically associated with neurological, digestive and renal disorders. Antibiotic treatment with erythromycin should be initiated as early as possible.

Adult↗
PubMed1980

[Epidemiology and prophylaxis of malaria in France (author's transl)].

A study of 100 cases of malaria in France, 98 of which were imported, shows the strong predominance (83%) of Plasmodium falciparum and of contamination in Africa (86%). The reasons why malaria is rare among tourists returning from Asia are given. The risk of re-introduction of the disease into France seems to be slight, especially for P. falciparum. Chemoprophylaxis is easy when aminoquinolines can be recommended, but much more complicated otherwise, the reasons for failure being the lack of effect of other drugs on pre-erythrocytic forms, resistance to chemotherapy and lack of information or carelessness.

Adult↗
PubMed1980

Human deficiency of the sixth component of complement in a patient with meningococcal meningitis and no haemostasis abnormality.

A case of human complete C6 deficiency is reported. The patient, a 31 year old white male, was seen on the occasion of an isolated episode of meningococcal meningitis. Serum complement hemolytic and bactericidal activities were lacking and could be restored to normal by addition of appropriate amounts of purified C6. No hemostatic abnormalities were observed.

Adult↗
PubMed1979

[Plasmodium ovale malaria in France. Probability of of genetic control of the incubation period (author's transl)].

Plasmodium ovale as the causative parasite in attacks of malaria is rare. Nevertheless, the number of cases seen in France would seem to be on the increase. In 137 attacks of malaria collected between 1967 and 1978, Plasmodium ovale was found on 13 occasions. The main characteristics of this form of malaria are, apart from its benign nature, the usual absence of any recurrence and a very variable incubation period, ranging from fifteen days to several months or even a year (with an average of 3.2 months). It is thus important to bear this diagnosis in mind, even if a long period elapsed since return from an endemic area, and it will be realised that adequate chemoprophylaxis using a schizonticide does not offer protection from forms with a long incubation period. Genetic control of the duration of the period of maturation of exo-erythrocytic forms, i.e. the incubation period, is suggested, identical to that recently advanced in the case of Plasmodium vivax. This would account for the variability and possible long duration of incubation periods. A usual monoclonal character of these infections could explain the virtual absence of recurrences.

Adolescent↗