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Biomedical subjects

R Bassermann

Publications and source records attributed to R Bassermann.

At least 19 recordsLinked to original sources
PubMed1996

[Multicystic peritoneal mesothelioma].

We report on a 31-year-old man with a 29 x 15 x 15 cm large abdominal tumor who came to surgery under suspicion of echinococcus cyst of the liver. Histologically, the neoplasm could identified as multicystic peritoneal mesothelioma (synonyma: benign cystic mesothelioma). Additionally some cysts were located in the greater omentum and mesocolon. In contrast to our case the benign cystic mesotheliomas most commonly occur in young women, localized in the pelvis and abdomen and often complicated by postoperative local recurrence. We performed a resection of the right hemicolon and the omentum. Postoperatively no further therapy was necessary because of the benign appearance of the lesion. Close follow-up is required in these patients due to the disposition for recurrences.

Adult↗
PubMed1993

Lipoatrophic diabetes.

Explore the source record for details and available documents.

Diabetes Mellitus, Lipoatrophic↗
PubMed1992

[Recurrent renal colic with passing of horny lamellae. A rare differential diagnosis of renal calculi].

A 64-year-old man reported left-sided renal colics recurring regularly every 5-10 months for the past 25 years. After a typical colic urinary sediment was found to contain brownish, flaky elastic material which histologically consisted of nucleus-free keratoid lamellae. Calcium concentration in serum and urine was normal, as were the serum parathormone (215 pg/l) and inorganic phosphate levels. The intravenous pyelogram revealed a polycyclicly circumscribed filling defect (15 x 20 mm) in the left renal pelvis. At ureteroscopy a lamellar brown-grey tumour was identified which arose from the medial wall of the pelvis. Histological examination demonstrated hyper- and parakeratotic hornified squamous epithelium without malignant degeneration. This finding suggested a cholesteatoma originating from squamous epithelial metaplasia. The tumour was removed endoscopically and the renal wall coagulated by laser, a procedure repeated after 3 months. The patient has been free of symptoms for 3 years.

Cholesteatoma↗
PubMed1992

Cytoreductive combination chemotherapy for regionally advanced unresectable extramammary Paget carcinoma.

Extramammary Paget carcinoma (EPC) is considered to originate from the eccrine and apocrine glands of the adnexal skin of the axilla, vulva or penis, scrotum, or perineum. If immunohistochemical techniques with the use of cytoskeletal markers are applied in addition to histologic examination, EPC lesions are found to be multifocal adenocarcinoma of the adnexal sweat glands. So far, therapeutic approaches have included primary surgery, followed optionally by radiation therapy. It is possible to achieve a cure only when manifestations are detected early and confined regionally. The role of palliative chemotherapy has not yet been assessed in this disease, particularly because of the lack of compliance and follow-up in patients with EPC.

Aged↗
PubMed1990

[Hutchinson-Horton ulcero-necrotizing cranial arteritis].

Arteritis cranialis ulcero-necroticans Hutchinson-Horton is the necrotizing variant of giant-cell temporal arteritis, which was first described by Hutchinson in 1890 and Horton in 1932. Although the histomorphological findings (occluding proliferation of the intima, destruction of the elastica interna, giant-cell infiltration) suggest reactive pathomechanisms, the aetiology of the disease remains rather uncertain. The hypothesis currently favoured is that auto-immunological processes originate from vascular alterations and subsequently lead to the recognition of antigenic determinants by the host immune system being followed by immunological response mechanisms clinically manifest as vasculitis. Arteritis cranialis is most frequently found in the temporal artery; however, the reasons for this preferential location are not clearly established, and giant-cell arteritis can also be found elsewhere. Ulceration of the skin can be encountered and may affect large areas of the scalp, depending on the vascular perfusion pattern involved. The case report described in this paper comprises anamnestic data, clinical and serological findings, and the histological picture typical for giant-cell arteritis. Stress is laid on the importance of early diagnosis to prevent irreversible complications with possibly fatal outcome.

Aged↗
PubMed1987

MRI of the breast--histopathologic correlation.

132 solid breast masses have been examined at our institution by MR and have consequently been histopathologically correlated. T1- and T2-weighted SE and multi-echo sequences have been evaluated visually. It was found that signal intensities of tissues on T2-weighted images correlated with the contents of fibrosis, cells or water. Thus in some lesions (which consisted of different tissue components), a characteristic internal structure was visible on T2-weighted images, reflecting their histopathologic structure. Corresponding to their different composition, differences of signal intensity have also been noted between those fibroadenomas with a high contents of fibrosis and all other well-circumscribed breast lesions (fibroadenomas, carcinomas). However, for the majority of lesions with irregular contours a discrimination based on signal intensities or calculated T1- and T2-values did not seem possible. This overlap can also be explained by the macroscopically similar composition (amount of fibrosis, water or cells) of benign and malignant irregular lesions.

Breast↗
PubMed1985

[Nuclear spin tomography in breast diagnosis].

The authors report about their preliminary experience with MRI in the diagnosis of breast disease. 50 breast masses in 41 consecutive patients have been evaluated by MRI and mammography, some of which have been evaluated by ultrasound, as well. All masses have consequently been biopsied. They include 32 carcinomas, 1 secondary malignant lymphoma, 4 fibroadenomas, 2 papillomas, 3 cysts, 1 hamartoma and 5 dysplastic nodules. Advantages and disadvantages of MRI of the breast are discussed. Possible future indications are suggested for selected cases.

Adenofibroma↗
PubMed1984

[Placental villous stem vessel occlusions. Studies of a twin placenta retained in utero following selective sectio parva].

During a twin pregnancy of a 41-year old woman, a selective sectio parva was performed, without removing the placenta, in the 23rd week of gestation. An amniotic fluid examination after routine amniocentesis showed a free trisomy 21 in only one of the twins. The twin with normal caryotype was delivered in the 28th week. His placenta was well developed, whereas the placenta of the other child showed severe obliterations of the stem arteries with partial avascularity of the villi. The histological aspect was that of a so-called "endarteritis obliterans". Since the twin delivered via sectio parva showed no signs of dystrophy, we presume that at the time of delivery his placenta had developed regularly. The changes of the placenta, demonstrated by histological examinations, seemed to be caused by the stopping of the foetal blood circulation. We suggest that the intrauterine death is not caused by "endarteritis obliterans" only as often described previously. Obviously, the morphological picture of endarteritis obliterans can be the result of cessation of foetal blood circulation. Obliteration of stem arteries might be the main reason for the stillbirth with significant signs of dystrophy. The similar histological picture in placentae of normally developed stillbirths is obviously caused by discontinuation of foetal blood circulation.

Adult↗
PubMed1983

[Comparison of mammography and automated sonography in 700 patients].

700 patients underwent routinely x-ray mammography and breast ultrasound with an automated grey-scale breast scanner. The parenchymal pattern of the ultrasound B-scan was morphological identical to the x-ray film. The echogram gave further informations about the topographic localisation of pathologic lesions to the chest wall including the pectoral muscles. The sonogram was of no value in 10 percent due to diffuse reflection of the breast. In cystic disease the diagnostic accuracy of the ultrasound was with about 100 percent superior to that of x-ray mammography. On the contrary the accuracy of the x-ray mammography was higher than that of ultrasound in the diagnosis of benign or malignant solids. Benign adenoma smaller than 1 cm could not be definetively recognised as carcinoma of this size. The diagnostic accuracy of the sonogram was 70 percent by 40 histologically proved carcinomas. The only use of the automated scanner in the diagnostics of the breast seams to be not justified, even not as a screening method, especially because small tumors with good prognosis are not recognized, however, the ultrasound gives additional important informations in the differential diagnosis of benign and malignant lesions of the female breast.

Adenofibroma↗
PubMed1981

Surface replacement of the hip. Experimental studies.

Surface replacement of the hip has been performed in 25 rabbits. Twenty animals were chosen for evaluation of the result of the operation after an average period of five months postoperatively. Tetracycline injections were given for fluorochrome labeling and radiographic controls have been made in vivo to check the position of the cup before the animals were sacrificed. Histological examinations were made from slides, which were gained after the metal cup had been removed with the bone cement still in place. It was found that the bone underneath the cup survived the surface replacement and that there was a normal metabolism further on. The trabeculae even grew into the surface structures of the inner layer of the bone cement and there was no interposition of membranes of fibrous tissue. It could be demonstrated that fibrous tissue between bone and bone cement is found only in cases of loosening of the cup and the cement or in cases of insufficient contact between this interface from the moment of the operation on. This is possible when air bubbles arise in the bone cement and get in contact with the trabeculae of the femoral head. Fluorochrome labeling proved the formation of new bone underneath the cup and the survival of the osseous structures of the coxal end of the femur. We believe, that in clinical cases it is necessary to remove all predamaged cancellous bone from the head of the femur (i.e. in cases of avascular necrosis) before the cup is attached. Close contact between the bone cement and the healthy spongiosa is one of the conditions for success in surface replacement of the hip.

Animals↗