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Biomedical subjects

R Bashir

Publications and source records attributed to R Bashir.

82 records · Page 5Linked to original sources
PubMed1987

The multiple manifestations of the encephalocraniocutaneous lipomatosis syndrome.

A case is reported of a recently described neurocutaneous syndrome, manifested by a noncommunicating right lateral ventricular cyst, a left-sided lipoma of the scalp with alopecia, right-sided multiple truncal lipomas, right-sided ocular manifestations, left leg hypertrophy, and seizures. The findings in cases of encephalocraniocutaneous lipomatosis are described to demonstrate the spectrum of this syndrome.

Adolescent↗
PubMed1987

Dynamic computed tomography of cerebral parenchymal tuberculomata.

The technique of intravenous dynamic cranial computed tomography has been applied to our patient population in Saudi Arabia in which parenchymal tuberculomata make up approximately 10-15% of all cerebral mass lesions. A spectrum of perfusion patterns was observed in tuberculosis progressing from presentation, through treatment, to resolution. These patterns reflect the microscopic vascular evolution of tuberculomata and parallel at least in part the effects of treatment. The method of dynamic scanning further demonstrates its value in improving the specificity of computed tomography in the evaluation of cerebral masses, thereby enhancing patient-beneficial triage.

Adolescent↗
PubMed1986

Cystic necrosis of the spinal cord in compressive cervical myelopathy: demonstration by iopamidol CT-myelography.

Seven consecutive patients with compressive cervical myelopathy were studied with standard water-soluble contrast myelography and immediate CT followed by delayed CT of the spinal canal at 10 to 12 hr. Every case demonstrated findings suggestive of necrosis and/or cavitation of the central portions of the spinal cord on the delayed CT study. Two types of abnormalities were visualized in the form of delayed collections of contrast media inside the cord: bilateral enhancement, a double-barreled "snake-eyes" appearance at or near the level of compression (consistent with central gray matter necrosis and/or cavitation--local syringomyelia ex-vacuo); and longitudinally oriented, "pencil-shaped" central enhancement of variable length distant from the level of compression (consistent either with an enlarged central canal--hydromyelia ex-vacuo--or with necrosis and/or cavitation extending craniad and caudad from the area of maximal compression and located in or near the anterior portion of the dorsal columns--distant syringomyelia ex-vacuo). These findings, supported by previous reports of autopsy specimens, may explain in part: the frequent discrepancy between the levels of maximal cervical compression and the variable neurologic signs; and the frequent lack of improvement in clinical signs after surgical decompression of the spinal cord at this late stage of the illness. We believe similar intramedullary lesions may be present in other cases of chronic compression of varying etiology at any location within the spinal cord.

Adult↗
PubMed1985

Syrinx of the conus medullaris and filum terminale in association with multiple hemangioblastomas.

A patient with multiple hemangioblastomas and syrinxes of the cerebellum and spinal cord is presented. An additional mass imaged at the L-3 vertebral level was identified by percutaneous syringography as a bilobular syrinx extending from the conus medullaris into the filum terminale. At surgery the syrinx was opened into the caudal cerebrospinal fluid space and the several hemangioblastomas excised. These spinal tumors all appeared to arise in juxtaposition to the posterolateral sulcus and dorsal sensory roots.

Adult↗
PubMed1985

Nervous system brucellosis: diagnosis and treatment.

We treated six patients with nervous system brucellosis causing polyradiculitis (2 patients), myelopathy (2), encephalitis (1), or meningitis (1). Diagnosis was based on Brucella species cultured from one patient, and a twofold or greater rise in antibody titer after therapy was started in the others. Treatment with trimethoprim-sulfamethoxazole with rifampin (5 patients) or tetracycline (1 patient) produced excellent clinical and laboratory response.

Adult↗
PubMed1984

Temporal appearance and distribution of the Ca2+ + Mg2+ ATPase of the sarcoplasmic reticulum in developing chick myocardium as determined by immunofluorescence labeling.

The temporal appearance and distribution of the Ca2+ + Mg2+ ATPase of the sarcoplasmic reticulum were determined in the developing chick heart (stage 9 to stage 16) by indirect immunofluorescence labeling. The results obtained showed that the Ca2+ + Mg2+ ATPase was first observed in the bulbus ventricular region of the single tubular heart at stage 9 to 10 of development, when these myocardial cells first contract. As the atrial and later the sinus venosus tissues became incorporated into the single tubular heart the Ca2+ + Mg2+ ATPase was also observed in these regions, however, the highest density of Ca2+ + Mg2+ ATPase labeling was generally observed in the region of the heart most recently incorporated. These results suggest that the sarcoplasmic reticulum is present and perhaps functional in the regulation of the cytoplasmic Ca2+ concentration and thereby the contraction-relaxation cycle in myocardial cells when the first contraction occurs, as well as throughout all subsequent stages of development. Furthermore comparison between the relative density and intensity of the Ca2+ + Mg2+ ATPase labeling and the intrinsic rate of contraction of the myocardial cells in the various regions of the heart (A. Barry, 1942, J. Exp. Zool. 91, 119-130) supports the possibility that a positive correlation exists between these two characteristics of the myocardial cells.

Animals↗
PubMedDate not supplied

Cerebral infarction in a young female following snake bite.

We present a normal 13-year old female who developed left cerebral infarction following envenomation by the carpet viper (Echis carinatus). We have read of only one other case of cerebral infarction following viper envenomation (Viperi russelli). Possible mechanisms for cerebral infarction in these circumstances are discussed. It is believed that this complication may be more common than is reported in the literature.

Adolescent↗
PubMedDate not supplied

The parenchymal CT myelogram: in vivo imaging of the gray matter of the spinal cord.

Past attempts to visualize the internal structure of the spinal cord in vivo have been hampered by many factors, including the small size of the cord, the dense bony investiture of the spine, and the similarities of tissue densities from one region to another within the cord. Delayed CT is the imaging technique currently being used at our institution as an adjunct to iopamidol myelography to visualize the deep gray matter of the cord. This visualization is achieved by a poorly understood differential gray/white-matter enhancement, possibly due to either a shielding effect of the white matter as it envelops the gray matter, a differential absorption rate between gray and white matter, or a greater rate of reabsorption of contrast by the more highly vascularized gray matter. This method is not being advocated as a primary diagnostic technique due to the lack of reliability in providing successful results from section to section, from patient to patient, and from one time period of delay to the next. Instead, it is an initial attempt to image the basic, intrinsic structure of the spinal cord in vivo, which may herald a valuable advance in imaging methodology.

Atrophy↗