Search PubMed⌕ Search

Biomedical subjects

R Barnes

Publications and source records attributed to R Barnes.

At least 127 records · Page 7Linked to original sources
PubMed1982

Efficacy of antipsychotic medications in behaviorally disturbed dementia patients.

This study compared the therapeutic efficacy of thioridazine, loxapine, and a placebo in the treatment of behavioral disturbances in nursing home patients with dementia. Antipsychotic medications were effective for the specific behavioral problems of anxiety, excitement, emotional lability, and uncooperativeness. Subjects with the most severe symptoms at baseline assessment derived the greatest benefit from treatment. Sedation, extrapyramidal symptoms, and decreased blood pressure were common side effects among patients treated with the antipsychotic drugs. The authors conclude that antipsychotic medication has a definite but limited therapeutic role in the treatment of behavioral disturbances in nursing home patients with dementia.

Aged↗
PubMed1981

Greenfield vena caval filter experience: late results in 156 patients.

In a review of clinical experience with the Greenfield filter in 156 patients, the most common indication for insertion was a contraindication to anticoagulation or recurrent embolism during treatment. Most of the filters (86%) were placed infrarenal, with 7% placed intentionally suprarenal and 7% misplaced but amenable to retrieval. Recurrent embolism was suspected in three patients (2%) on the basis of symptoms and was diagnosed by scan in three patients (2%). Follow-up studies on 119 local patients (11 were lost, 49 died) extended to 63 months (average, 23 months) and showed no migration or deaths due to recurrent embolism. Of 102 venacavograms obtained, occlusion of the cava was seen in only three patients (5%), for a long-term patency rate of 95%.

Adolescent↗
PubMed1981

Depression in older persons: diagnosis and management.

Depression is a common psychiatric disturbance of late life that is frequently not recognized by nonpsychiatric physicians. Confusion in psychiatric nosology, variability in clinical presentation, increased frequency of medical disease and medication use and cultural biases toward older persons complicate the diagnosis. Detection of depression is important because often this disorder can be successfully treated.

Adult↗
PubMed1980

Complications of transurethral resection of bladder tumors: prevention, recognition and treatment.

Between 1931 and 1971, 373 patients underwent transurethral resection of bladder tumors for cure or for control of the neoplasms. Complications included perforation of the bladder wall (5 per cent), hemorrhage requiring transfusion (13 per cent), infection (24 per cent) and postoperative mortality (1.3 per cent). Patients in whom perforations occurred had approximately twice as many infections and twice as much hemorrhage as the entire group but there were no postoperative deaths of those with perforations. Morbidity and mortality can be reduced in patients with perforation by 1) using isotonic irrigating fluid, 2) avoiding over-distension of the bladder, 3) maintaining postoperative free drainage through the catheter and 4) diagnosing and treating hyponatremia.

Hemorrhage↗
PubMed1979

Fibrous contracture of bladder neck: cause, prevention, and treatment.

Through a retrospective study of bladder neck contracture it was found that bladder neck resection and incision were equally effective for treatment of postoperative bladder neck contractures. It was also found that incising the bladder neck at the end of transurethral resection of the prostate (TURP) did not cause vesicoureteral reflux and did not improve the incidence of postoperative bladder neck contracture.

Contracture↗
PubMed1979

Effects of acute hemodynamic alterations on pulmonic valve motion. Experimental and clinical echocardiographic studies.

The purpose of this study was to assess the effects of acute alterations of the pulmonary circulation on the pulmonic valve echocardiogram. We measured the pulmonic valve opening velocity (PVOV) and right-sided systolic time intervals (right ventricular preejection period-to-right ventricular ejection time ratio [RPEP/RVET] in 22 open-chest dogs subjected to acute hemodynamic alterations produced by inferior vena cava constriction, atrial pacing, isoproterenol infusion and microsphere embolization of the pulmonary artery. We found only fair correlations between PVOV and peak pulmonary artery flow (r = 0.56), right ventricular dp/dt (r = 0.43), stroke volume (r = 0.42), pulmonary artery systolic pressure (r = 0.33) and peak pulmonary artery acceleration (r = 0.31). RVET was shortened by reduced venous return (caval constriction) and by increases in heart rate (atrial pacing and isoproterenol), which resulted in increases in RPEP/RVET that did not correspond well to simultaneous changes in pulmonary artery pressure. In seven patients breathing 10% O2 to raise pulmonary artery pressure acutely, we found no change or a fall in PVOV. Thus, the pulmonic valve echocardiogram is influenced by multiple factors relating to parameters of pulmonary flow and right ventricular contractility, and may be of limited clinical usefulness in predicting pulmonary artery pressures.

Animals↗
PubMed1977

Changes in grade and stage of recurrent bladder tumors.

A retrospective study with adequate followup of 5 years of longer of 114 patients who had transurethral resection for cure or control of bladder tumors and in whom there were 1 or more recurrences is reported. There was recurrence of the tumor in a higher grade in 19 per cent of the cases and in a higher stage in 22 per cent. The interval between the treatment of the original tumor and a recurrence in a higher grade or state varied from 0.25 (3 months) to 27 years. When a low grade or low stage tumor recurs in a higher category in less than 3 years more aggressive treatment should be considered.

Follow-Up Studies↗
PubMed1976

Forty years of transurethral prostatic resections.

The 4 consecutive series of transurethral prostatic resections compared were done by the senior authors during a period of nearly 40 years: 420 cases in 1937 to 1938, 520 cases in 1940 to 1945, 480 cases in 1950 to 1955 and 270 cases in 1972 to 1973. The most notable improvements in the recent series are the fewer patients with temperatures more than 100 degrees (69 virsus 29 per cent) and the improved mortality rate (5.5 verus 0.7 per cent). In our opinion these improvements are owing to antibacterial medication, improved instruments, more skillful performance of the operation, the use of isotonic irrigating fluid and improved postoperative care.

Fever↗
PubMed1976

Early carcinoma of the prostate: comparison of stages A and B.

Stage A--occult, latent, preoperatively undiagnosed, incidentally found, stage I or T0--carcinoma of the prostate has been considered to be an earlier stage than stage B--II, T1 or T2, palpable nodule. In a comparative study of 118 patients with stage A lesions and 115 patients with stage B lesions we have found more focal lesions in A than in B. The A lesions were also less highly malignant than the B. However, the survival of patients with A lesions was a little less than those with B lesions. Age differences and more extensive growth before a detection may account for the differences. Patients with diffuse lesions and those with the more highly malignant lesions had a shorter survival than those with focal lesions and with a lower grade of malignancy in stages A and B. All available preoperative diagnostic data and a through histopathological examination of the surgical specimen are necessary to accurately stage prostatic carcinoma. Other well recognized diagnostic tests, such as the lymphangiogram, acid phosphatase value bone scan and so forth, are also necessary to accurately assess the extent of the disease.

Aged↗
PubMed1976

Variations of pulmonary function amongst workers in cotton mills.

Lung function studies and clinical examinations of 493 workers in eight cotton mills in New South Wales revealed 12 workers with byssinosis. The reasons for the low incidence of byssinosis in view of relatively high cotton dust in air concentrations are discussed briefly.

Air Pollutants, Occupational↗