[Burckhardt's vernal photodermatosis].
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Adult↗
Biomedical subjects
R Baran
Publications and source records attributed to R Baran.
[Proximal nail fold biopsy in connective tissue diseases. 26 cases studied under light and electron microscopy and direct immunofluorescence (author's transl)].
30 specimens of nail fold biopsies have been studied through light and electron microscopy, and direct immunofluorescence, in 26 cases of connective tissue diseases: Raynaud's phenomenon and acrosclerosis (7 cases), systemic scleroderma (10 cases), chronic and acute lupus erythematosus (4 cases), dermatomyositis (5 cases). Numerous tissular changes have been observed by these three different ways: capillaries dilatations, dermal sclerosis, numerous, large, dermal and epidermal colloid bodies, basal lamina replications, collagen's modifications, tubuloreticular inclusions, crystalloid bodies, lysosomial inclusions, immunoglobulins deposits. Thus proximal nail fold appears to be an elective tissular area for collagen diseases study.
Capillaries↗
[Normal proximal nail fold structure (author's transl)].
Normal structure of nail fold capillaries as observed by capillaroscopy and fluoroscopy is recalled. A procedure of proximal nail fold biopsy is described. The technique is simple without disadvantage for patients. Tissue from the proximal nail fold is studied in three different ways: light microscopy with histochemistry, electron microscopy and direct immunofluorescence. In the two normal cases studied, usual epidermal and dermal components are found. Some particular point may be emphasized: sweat's droplets draining of distal part of proximal nail fold, numerous and large nervous structures, capillaries basal lamina multiplication.
Adult↗