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Biomedical subjects

R B Wescott

Publications and source records attributed to R B Wescott.

At least 55 records · Page 3Linked to original sources

Anthelmintic efficacy of mebendazole for pinworm infection of mice.

A series of 6 experiments was conducted to test the efficacy of mebendazole in eliminating naturally occurring pinworm infections from mice. Subjects treated with from 40-500 mg/kg of the drug harbored markedly fewer parasites than untreated controls. Treatment at 10 mg/kg appeared to be less effective. No mortality or overt signs of toxicity were observed in any of the experimental subjects.

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The influence of filter top caging on the transmission of pinworm infections in mice.

The effectiveness of filter top cages in preventing infection of mice with pinworms, Aspiculuris tetraptera and Syphacia obvelata, was investigated by introducing mice from a pathogen-free colony into a colony in which both types of pinworms were enzootic. Half of the pathogen-free mice were maintained in filter top cages, while the remainder were held in similar cages without filters. All mice thus introduced were killed and examined after 3-8 week exposure periods. No pinworm were recovered from mice in 17 of 18 cages with filter tops while mice in 12 of 16 cages without filter tops were infected.

Animals↗

Internal parasites of Washington cattle.

The occurrence of internal parasites in Washinton cattle was estimated. During the survey period in 1972 and 1973, more than 3,700 fecal samples from 29 herds and 4 feedlots, and viscera from 55 cattle were examined. The percentage of fecal samples with parasite eggs or oocysts from herds was as follows: oocysts, 77%; "strongyline" eggs, 44%; Nematodirus eggs, 3%; Moniezia eggs, 3%; Fasciola eggs, 2%; Trichuris eggs, 2%; and Dictyocaulus larvae, 1%. The fecal samples from feedlots contained principally strongyline eggs which varied markedly in numbers among groups of cattle in the lots. The predominant parasite in viscera was Ostertagia spp, which was recovered from all of the cattle examined. Other parasites identified in the survey were found less frequently in these examinations. Cattle in dairy and beef operations utilizing irrigated pastures were particularly prone to Fasciola infections, and more strongyline eggs were observed there than in fecal samples from other management systems. Seasonal fluctuations in numbers of strongyline and Fasciola eggs were pronounced.

Animals↗

Distribution of bacteria in feces of swine.

A new technique is described for evaluating bacterial cell distribution in fecal samples. Spatial relationships of cells within an area rather than number of cells per unit volume or weight are measured by this technique. Measurements of cell distribution by this method indicated that bacteria occurred in freshly voided swine feces as pure, discrete colonies rather than as single cells distributed randomly or uniformly throughout the sample.

Animals↗