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Biomedical subjects

R B Roberts

Publications and source records attributed to R B Roberts.

144 records · Page 8Linked to original sources
PubMedDate not supplied

Viridans streptococcal endocarditis: the role of various species, including pyridoxal-dependent streptococci.

The viridans streptococci are a heterogeneous group of organisms frequently associated with microbial endocarditis. Isolates from consecutive patients with endocarditis due to viridans streptococci who were seen at The New York Hospital from 1944 to 1955 and from 1970 to 1978 were speciated, and the relative frequencies and patterns of sus ceptibility to penicillin were determined. Vitamin B6-dependent streptococci, classified as Streptococcus mitior, accounted for 5%-6% of microbial endocarditis in both time periods. Since these nutritional variants require the active forms of vitamin B6 for growth in routein media, they can be responsible for culture-negative endocarditis. Media must be supplemented with either pyridoxal hydrochloride or pyridoxamine dihydrochloride (the active forms of vitamin B6) for isolation, identification, and subsequent testing of susceptibility to antimirobial agents. Pyridoxine hydrochloride does not support the growth of these organisms in vitro.

Endocarditis, Bacterial↗
PubMedDate not supplied

Maintenance of body temperature by heated humidification.

Though difficult to prove conclusively, humidification of anesthetic gases during prolonged surgery appears beneficial. Even slight falls in body temperature are detrimental, causing significant increases in O2 consumption in the immediate postoperative period. A new heated humidifier which supplies gases at 100% relative humidity at 35 degrees C at the patient inlet has been used both to supply humidity and to prevent a fall in interoperative temperature. This was successfully employed in 19/25 prolonged procedures. The warmed humidified gases contributed significantly to the maintenance of homeostasis during anesthesia.

Adolescent↗