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Biomedical subjects

R Askenasi

Publications and source records attributed to R Askenasi.

At least 37 records · Page 2Linked to original sources

Pneumococcal cellulitis.

A 42-year-old man with pneumonia was admitted for rhabdomyolysis. Streptococcus pneumoniae was isolated from the cellulitis surrounding the muscular necrosis. Subcutaneous localisation of S. pneumoniae in the course of a septicemia has never been described, although rhabdomyolysis may be associated with bacterial infections.

Adult↗

What is emergency? Analysis of a population presenting to an emergency room.

The population presenting at emergency rooms is increasing in Belgium. What is emergency in 1983 and why do people come? From a study of the emergency room population in a relatively new university hospital it emerges that more than 30% of those patients are in critical conditions or require in hospital treatment and about 50% are in acute discomfort. Our results confirm the impression that inappropriate use of emergency rooms is more an impression than a real problem. For socio-economic and cultural reasons, people go to emergency rooms when they need or think they should have medical help. Some emergency rooms are well able to cope with this situation. Others, less well-equipped in staff and facilities are dangerous and should be improved or closed. Unfortunately education and training programs for emergency physicians are still unknown in many parts of the French-speaking Belgium.

Adult↗

Naloxone and alcohol intoxication in the dog.

1 The effects of naloxone upon ethanol-induced coma have been investigated in dogs. In a double blind study, 15 mongrel dogs received ethanol i.v. (4 g/kg) followed by a single dose of naloxone (12 micrograms/kg). 2 Naloxone failed to affect either the duration of respiratory arrest or the time to recovery of motor coordination. In similar animals treated with the narcotic analgesic, fentanyl, naloxone induced a dramatic and complete reversal of the narcotic effects within 30 seconds. 3 It is concluded that, if naloxone has any effect in alcoholic coma, it is not comparable with its dramatic action in narcotic coma.

Alcoholic Intoxication↗

Value of lithium plasma concentration in severe lithium intoxication.

Lithium intoxication is a frequent condition with sometimes severe symptoms. Despite repeated plasma measurements, it is not always possible to prevent serious side effects because they can occur at therapeutic plasma levels. Several aspects of the lithium metabolism are reviewed and illustrated by two case reports.

Adult↗

Naloxone and ethanol intoxication.

Naloxone has been said to be an antidote of acute ethanol intoxication in man. Experimental and clinical studies are however not convincing and contradictory. We have used naloxone to antagonize the effect of ethanol in mice. Results are compared to those obtained with morphine intoxication. Even at high doses (5 mg/kg) naloxone is not a good antagonist of ethanol intoxication in mice.

Alcoholic Intoxication↗

[Seizures due to lithium intoxication (author's transl)].

Lithium intoxication may present as seizures, which have been observed when plasma lithium concentrations were decreasing. The neurotoxic effect of lithium could be due to a rise in intra-/extra-cellular lithium ratio. Intracellular retention of lithium reflected in rapid fall of plasma concentrations during treatment would modify cell membrane properties and increase neuronal excitability. Such a mechanism would explain the occurrence of seizures despite therapeutic plasma lithium concentrations.

Adult↗