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Biomedical subjects

R Arora

Publications and source records attributed to R Arora.

At least 307 records · Page 17Linked to original sources

Follow-up of balloon aortic valvuloplasty in young adults--a combined hemodynamic and Doppler echocardiographic study.

Percutaneous Balloon Valvuloplasty was performed in 25 patients with severe aortic stenosis (Aortic valve area index: 0.23 to 0.70, mean 0.36 +/- 0.11 cm2/m2). The mean age was 23 +/- 15 (range 6-66) years, and majority (n = 18) had noncalcific valves. Valve morphology was bicuspid in 14, tricuspid in 6 and indeterminate in 5. Valvuloplasty resulted in a fall of peak systolic gradient (PSG) from 112 +/- 35 to 34 +/- 16 mmHg (p less than 0.001), and an increase in aortic valve area (index) (AVAI) from 0.36 +/- 0.11 to 0.82 +/- 0.43 cm2/m2 (p less than 0.001). Follow-up data at 16 +/- 6 months were available for 18 patients, 80 per cent of whom registered symptomatic improvement. Repeat catheterization, performed in 12 cases, showed increase of PSG to 53 +/- 22 mmHg and a fall in AVA (1) to 0.62 +/- 0.24 cm2/m2, as compared to the results immediately following the procedure. In addition, 3 patients had their valve areas estimated by doppler echocardiography. Forty-six per cent of these 15 patients (n = 7) showed evidence of restenosis. Four out of these 7 cases had calcific valves, whereas none of the patients who had sustained improvement had calcification. Tricuspid morphology was present in 50 per cent of the group with sustained improvement, as compared to 20 per cent of the group that restenosed. Our preliminary data shows sustained hemodynamic improvement after balloon dilatation in young patients with severe aortic stenosis with noncalcific and tricuspid aortic valve.

Adolescent↗

Massive congenital submitral aneurysm of the left ventricle: a case report.

Subannular left ventricular aneurysm adjacent to the mitral valve is a rare entity predominantly seen in the young blacks. A young Indian patient with massive submitral left ventricular aneurysm (10.6 cm x 7.5 cm) presenting with congestive heart failure is reported with 2D-echocardiographic, haemodynamic and cineangiographic and pathologic data.

Adult↗

Detection of multivessel coronary artery disease by early exercise testing after first myocardial infarction.

The ability of a symptom limited treadmill exercise test (TMT) to predict the presence of multivessel coronary artery disease (MVD) three weeks after a first myocardial infarction was assessed in 76 male patients aged 25-65 (mean 40.9 +/- 10.1) years. There were 6 patients with normal coronaries, 36 with single vessel disease (SVD), 20 with double vessel disease (DVD), and 14 with three vessel disease (TVD). TMT was positive in 20/34 (58.8%) patients with MVD, and 4/42 (9%) patients with SVD or normal coronaries. The predictive accuracy of a positive TMT in detecting MVD was 83.3%, and the predictive accuracy of a negative TMT in excluding MVD was 73.1%. It is concluded that TMT is useful test for predicting the presence or absence of MVD in survivors of a first transmural myocardial infarction.

Adult↗

Dominant right ventricular dilated cardiomyopathy: clinical, echocardiographic and haemodynamic profile.

Ten patients of dominant right ventricular dilated cardiomyopathy (RVDCM) seen over a period of three years in this institution are described. There were six males and four females in the age range of 6.50 years. Presenting features were right ventricular failure (7), paroxysmal supraventricular tachycardia (2), and one patient was detected on routine chest skiagram. All patients had characteristic electrocardiographic and radiologic features. 2D-echocardiographic examination revealed enormous dilatation of right atrium, ventricular cavity and outflow tract, interatrium and ventricular septum concave to the right, pre-systolic pulmonary valve opening, small left atrium and ventricle. Pulsed doppler echocardiogram revealed varying degree of tricuspid incompetence in all. Four patients underwent haemodynamic and cineangiographic studies showing left ventricular involvement in one. The patients have been followed up on digitalis, diuretics and quinidine with variable response to treatment. One patient died of uraemia, and one female patient recovered completely following delivery. Dominant RVDCM is a distinct clinical entity with typical features and with typical features and ill-defined natural history.

Adult↗