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Biomedical subjects

R Arora

Publications and source records attributed to R Arora.

At least 217 records · Page 12Linked to original sources

Lumbar canal stenosis.

Lumbar canal stenosis has been well recognised as a cause of low backache. A study was undertaken to find out the incidence of lumbar canal stenosis in Indian adults from 1 July 1978 to 30 June 1981. The diagnosis was based on clinical, radiological and myelographic findings. The majority of adults in the fourth decade were found to be suffering from degenerative arthritis of the apophyseal joints with thickened ligamentum flavum. Congenital stenosis cases were few. Decompression of the stenosed canal by laminectomy of the stenosed segments and excision of thickened ligamentum flavum, or any osseous element in the posterolateral compartment, gave lasting relief from backache and intermittent claudication. Incidence of pure relative stenosis is higher than pure absolute stenosis amongst Indian adults.

Adult↗

Uhl's anomaly with rudimentary pulmonary valve leaflets: a clinical, hemodynamic, angiographic, and pathologic study.

An acyanotic 4-year-old male child who failed to thrive presented with signs of persistent right heart failure and no cardiac murmurs. There was radiologic evidence of gross cardiomegaly with unremarkable lung fields. Cardiac catheterization and cineangiographic features helped in arriving at the diagnosis of parchment right ventricle with normal tricuspid valve (Uhl's anomaly), a rare condition seldom diagnosed during life. The patient was subjected to surgery, and Glenn's operation was performed, following which he died of a low output state and bradyarrhythmia. Autopsy revealed partial parchment right ventricle with rudimentary pulmonary valve leaflets, a combination not described previously.

Child, Preschool↗

Comparison of platelet count and platelet protein methods for determination of platelet MAO activity.

Platelet monoamine oxidase (MAO) activity in 10 normal volunteers was studied as a function of platelet protein or electronically-determined platelet counts. Comparisons of the two methods were made for samples assayed on the same day as well as one week later. The MAO activities resulting from both methods were significantly correlated and reproducible but the results of the platelet count method were, in most instances, slightly but significantly more reliable than the platelet protein method. The relevance of these results to the controversy concerning platelet MAO activity in schizophrenia is discussed.

Blood Cell Count↗

Sex differences in chronic cor pulmonale in delhi.

Chronic cor pulmonale is more prevalent in northern India than in the south. It is equally common in men and in women and accounts for 20% of all admissions for heart disorder in Delhi. In a study of 766 patients (239 men and 527 women) carried out over a 15-year period there were some striking sex differences. Some 75% of men and 10% of women smoked. The women came from the poorest class and all of them cooked from an early age over smoky and primitive fireplaces in ill-ventilated huts, while only 7% of the men cooked their own food. Chronic bronchitis and bronchiectasis were the commonest associated lung disorders in both sexes. The women developed heart failure 10-15 years earlier and showed more severe congestive failure with larger hearts and greater derangement of pulmonary function. It is concluded that the cause of chronic cor pulmonale in women in Delhi was damage to the lungs from exposure to smoky cooking fuels from girlhood onwards, followed by repeated chest infections.

Adult↗

Physiology of the epididymis and induction of functional sterility in the male.

The factors regulating the physiology of the epididymis and the induction of functional sterility by alteration of epididymal function are discussed. The threshold requirement of androgens to maintain the structural and functional integrity of the epididymis in the rat, hamster and monkey is much higher than that needed by the accessory glands. Further, the cauda epididymidis has a higher threshold requirement of androgens than the caput epididymidis and may reflect the differences in the availability and metabolism of androgens to these two segments. An inverse relationship exists between the levels of sialic acid (sialoproteins) in the epididymal luminal plasma and that bound to the spermatozoa in the cauda epididymidis. Androgen deprivation and consequent alteration of the secretory activity of the epididymis either by castration or by treatment with antiserum to LH or by the antiandrogen, cyproterone acetate, caused concurrent decrease in the levels of sialic acid in the luminal plasma and in the spermatozoa of the different regions of the epididymis. These changing patterns of sialic acid in the spermatozoa and luminal plasma may be associated with changes in the surface charge of the spermatozoa and the stabilization of the acrosome and its membranes during sperm maturation.

Androgens↗