Search PubMed⌕ Search

Biomedical subjects

R Ammann

Publications and source records attributed to R Ammann.

At least 127 records · Page 7Linked to original sources

Quantitative assessment of duodenogastric reflux after vagotomy with or without pyloroplasty-A clinical investigation.

The experiment consists in intravenous infusion of 99mTc-Hepatobida, fractioned aspiration of the gastric juice by means of a tube and measurement of radioactivity in the aspirated liquid. Patients are fasting for at least twelve hours and tests are started early in the morning. 5 mCi of 99mTc-Hepatobida are injected intravenously. Thereupon gastric juice is collected by means of a gastric tube every ten min during 90 min. Duodenogastric reflux is provoked by installing 100 ml of Intralipid. Sampling of gastric contents is continued as above. Radioactivities in the aspirate are compared in five patients before operation, after truncal vagotomy with pyloroplasty, after highly selective vagotomy without pyloroplasty and after highly selective vagotomy without pyloroplasty. There is no typical pattern for either type of operation. We suggest that motor antral activity is more important than pyloric function.

Bile Reflux↗

[PABA test versus chymotrypsin and fat determinations in the stool in pancreatic functional diagnosis].

32 patients with proven chronic pancreatitis and 56 controls without evidence of pancreatic disease were studied by the PABA test, the fecal chymotrypsin method and the fecal fat method. The sensitivity of the fecal chymotrypsin method for detection of pancreatic disease was significantly higher (p less than 0.005). The sensitivity of the PABA test and the fecal fat method were comparable. The specificity of the PABA test and the fecal chymotrypsin method was of the same order.

4-Aminobenzoic Acid↗

[Chemotherapy of human echinococcosis with mebendazole (Vermox): preliminary clinical results].

Two patients with inoperable multiple Echinococcus granulosus infections involving the lungs and the liver (one patient) were treated with the following daily doses of mebendazole (Vermox): 3 days 1000 mg, 3 days 1500 mg, the following 3 months 30-40 mg/kg body weight. One of the patients had been treated before with mebendazole in similar doses for 3 periods of 5-6 weeks each. The patients received the drug as 500 mg tablets divided into 3 daily doses after meals. After termination of treatment a distinct regression of lung cysts was demonstrable in both patients, with the exception of one cyst. The liver cyst in one of the patients had also decreased in size. About 8 months after therapy signs of reactivation of lung cysts were observed in one patient, and a new course of mebendazole treatment was therefore started.

Adult↗

[Pseudocysts and retention cysts in acute and chronic pancreatitis (author's transl)].

42 cases of pancreatic cyst in acute (22 cases) pr chronic (20 cases) pancreatitis were seen between 1962 and 1976. Analysis of the case data revealed the following: (1) exact assignment of the cyst to acute or chronic pancreatitis is often possible only by long-term observation; (2) the cysts of chronic pancreatitis are not a uniform group: some (8 cases) apparently occurred in acute pancreatitis through necrotic episodes (pseudocysts), others (12 cases) by a retention mechanism; these "retention cysts" develop later in the course of chronic pancreatitis than the pseudocysts and produce a different clinical picture with better prognosis; (3) barium meal and retrograde cholangiopancreatography proved of diagnostic value' (4) if the cysts persist for more than six weeks operation is indicated because of the high incidence of complications.

Acute Disease↗

A double-blind trial of synthetic salmon calcitonin in the treatment of acute pancreatitis.

A multicenter randomized double-blind trial on the use of synthetic salmon calcitonin (SCT) was carried out in 94 patients with acute pancreatitis. In addition to strict standard treatment--without aprotinin, atropine, or antacids--50 patients received daily 3 x 20 micrograms = 300 MRCU SCT intravenously and 44 patients received placebo for 6 days. Mortality rate was not influenced, overall mortality being 5.3%. The number of patients without pain and with normalized serum amylase on a given day was significantly higher in the group treated with SCT. Other parameters such as doses of analgesics, leukocyte count, and normalization of seven defined clinical and laboratory criteria within 6 days showed a positive trend without reaching significance.

Acute Disease↗

[Chlamydia peritonitis: a disease of young females].

Serological evidence of recent infection with Chlamydia trachomatis was found in 9 of 11 young women with acute peritonitis or perihepatitis proved by laparoscopy. High antibody titres to chlamydiae without laboratory evidence of gonococcal infection were present in 5 of these 9 patients, while the other 4 had evidence of simultaneous gonococcal infection. C. trachomatis may play an important part in peritoneal inflammation previously attributed only to gonococci.

Adult↗