Search PubMed⌕ Search

Biomedical subjects

R Adar

Publications and source records attributed to R Adar.

At least 91 records · Page 5Linked to original sources

Distribution and symmetry of arteriosclerotic lesions of the lower extremities: an arteriographic study of 200 limbs.

Lower-extremity arteriograms of 100 candidates for vascular surgery were reviewed. All the arteries in the 200 limbs were visualized and graded as normal, irregular, stenotic, or occluded. The occurrence of hemodynamically significant disease (stenosis or occlusion) was markedly different in various arteries: iliac--37%, common femoral--9%, superficial femoral--58%, deep femoral--19%, popliteal--17.5%, tibialis anterior--27.5%, tibialis posterior--28.5%, and peroneal--16.5%. A remarkable symmetry was observed between the two lower limbs. In 53-76% of contralateral vessels the arteriographic picture was identical. When one degree of difference in arteriosclerotic involvement was allowed, the symmetry increased to 80-96%.

Angiography↗

Iliopsoas injury in soccer players.

Injuries to the iliopsoas muscle are rarely mentioned in the literature dealing with soccer-related trauma. This report describes our experience in the successful diagnosis and treatment of iliopsoas injury in 40 professional soccer players. These injuries were not associated with direct external trauma to the muscle. Anatomical and functional characteristics of the iliopsoas are reviewed as they relate to the diagnosis and to the treatment by direct local injection with corticosteroids. A safe anatomical approach to the iliopsoas below the inguinal ligament is described.

Adrenal Cortex Hormones↗

Hemorrhagic complications encountered on a surgical service. A 7 year survey.

An analysis of 205 episodes of bleeding encountered during a 7 year period by the staff of a surgical service has been described. Of 168 postoperative bleeding episodes, 80 were associated with anticoagulant or antiaggregant treatment, 51 were caused by technical error, and 37 were associated with sepsis. Of 18 hemorrhages after invasive procedures, 12 were associated with anticoagulants. In the whole series, in 33 of 111 episodes in patients receiving antithrombotic drugs, there was some deviation from standard accepted protocols. Bleeding occurred in the surgical wound or at the site of operation or puncture in 154 instances. Some of the bleeding episodes, especially at other sites, presented in an unusual manner and posed a diagnostic problem. Bleeding was responsible for death or contributed to death in 11 patients, and in 32 patients, it caused operation or reoperation. Other short- and long-term morbidity was also caused. As in many complications, prevention is of the essence.

Adult↗

Computerized tomography in the diagnosis of congenital hepatic fibrosis.

A case of congenital hepatic fibrosis (CHF), a relatively rare disease, was diagnosed preoperatively on the basis of clinical and radiological findings. The diagnosis was confirmed by computerized tomography and later proven by a liver biopsy performed during cholecystectomy. Increased awareness of this entity may reveal heretofore unidentified cases of CHF.

Adult↗

Cellular sensitivity to collagen in thromboangiitis obliterans.

We studied 39 patients with thromboangiitis obliterans to determine their cellular and humoral immune responses to native human collagen Type I and Type III, which are constituents of blood vessels. Cell-mediated sensitivity to these collagens was measured by an antigen-sensitive thymidine-incorporation assay. The mean stimulation index--the ratio of thymidine incorporation in the presence of antigen to that in its absence--with both Type I and Type III collagens used as antigens was significantly higher in patients with thromboangiitis obliterans than in patients with arteriosclerosis obliterans or in healthy male controls. Lymphocytes from 77 per cent of the patients with thromboangiitis obliterans exhibited cellular sensitivity to human Type I or Type III collagens (or both). Furthermore, in 17 of 39 serum samples from the patients with thromboangiitis obliterans a low but significant level of anticollagen antibody activity was detected, whereas there was no antibody activity in serum samples from controls. These results suggest that there is a distinct etiologic factor in this disease and also raise the possibility of differentiating between thromboangiitis obliterans and arteriosclerosis obliterans by immunologic means.

Adult↗

Cardiac complications in vascular procedures: comparison of percutaneous angioplasty and surgery.

Percutaneous transluminal angioplasty (PTA) is currently recommended to high risk cardiac patients as a relatively safer procedure compared to reconstructive peripheral vascular surgery (RPVS). In order to evaluate this approach we studied the incidence of cardiac complications in 86 consecutive patients undergoing peripheral vascular procedures. 45 patients (Group I) underwent RPVS and 41 (Group II) PTA. The two groups were comparable regarding age, sex, the location of vascular lesions, the incidence of previous MI (Group I--40%, Group II--46%), and the incidence of angina pectoris (I--25%, II-29%). No special treatment or monitoring was used for patients with ischemic heart disease (IHD) in the PTA group. Successful revascularization was achieved in 36 (80%) of the surgical patients and 25 (61%) of the patients who underwent PTA. There were two anginal attacks, two MIs, and one cardiac death in group I compared to six anginas, three MIs, and one death in Group II. These differences are not statistically significant. It is concluded that PTA carries a definite risk of cardiac complications in patients with known IHD.

Aged↗

The effect of ischemia of the dog's colon on transmural migration of bacteria and endotoxin.

The purpose of this investigation was to evaluate the effect of temporary ischemia created during the surgical preparation of the colon for resection on transmural migration of bacteria and passage of endotoxin through the ischemic wall of the canine colon. Eighteen dogs were used: in fourteen the colon was devascularized by ligating all marginal vessels. Aerobic and anaerobic cultures and washings for endotoxin assay were obtained from the surface of the bowel at intervals up to 6 hr after creating the ischemia. Peripheral and portal blood samples were also obtained at equal intervals for bacteriologic cultures and endotoxin assay. Bacterial transmural migration was examined in 10 dogs. In 6 of the dogs biologically marked bacteria were introduced into the colon via a rectal catheter before producing the ischemia. In 4 dogs radioactively labeled endotoxin was introduced into the colon in a similar fashion. In all the dogs, surface cultures, both routine and specific for the marked bacteria, were negative for the whole period of up to 6 hr after creation of ischemia. All portal and peripheral vein cultures were also negative. Transmural migration of endotoxin was investigated in 8 dogs, 4 of which served as controls and underwent a sham operation. In the 4 dogs in which the colon was devascularized endotoxin was discovered in peritoneal washings, and in portal and systemic blood samples, as early as 30 min after the preparation of the bowel was completed. In the control dogs endotoxin assays were negative throughout the experiment. In this model up to 6 hr of ischemia did not result in migration of bacteria through the ischemic wall. Endotoxin, however, entered the peritoneum and the blood very soon after producing the ischemia.

Animals↗

Aortic false aneurysm following blunt trauma of the abdomen.

A post-traumatic false aneurysm of the abdominal aorta was diagnosed 8 years after blunt abdominal trauma with blast, sustained during combat. Severe persistent backache with erosion of D12 and L1 vertebrae were the presenting symptoms. The aneurysm was repaired by tube graft replacement.

Abdominal Injuries↗