Search PubMed⌕ Search

Biomedical subjects

R Abraham

Publications and source records attributed to R Abraham.

185 records · Page 11Linked to original sources
PubMedDate not supplied

The rat man revisited: comments on maternal influences.

Freud's case study of an obsessive young man, published in 1909, has provided the foundation for the psychoanalytic understanding of obsessive illness. Freud reported the case in Oedipal terms, viewing the patient's symptoms as arising from his fear of castration by his father as punishment for his sexual desires. Freud's working notes on the case, however, contain much material about the women in Lorenz's life not included in the published case or in Freud's formulation. Careful review of this data suggests that important aspects of Lorenz's obsessive disorder harken back to conflicts in his relationship with his mother. This reexamination of Freud's classical case suggests that these questions concerning the genesis of obsessive dynamics should be further explored.

Adult↗
PubMedDate not supplied

Dietary carbohydrates and synthesis and secretion of apolipoprotein B-containing lipoproteins in rat hepatocytes.

The influence of glucose-, sucrose- and starch-containing diets on the synthesis and secretion of lipoprotein in the density range of very-low-density lipoproteins (VLDLs) and low-density lipoproteins (LDLs) was studied via primary cultures of rat hepatocytes. Apolipoprotein B secreted by hepatocytes from rats fed a sucrose diet was significantly more than in rats fed starch or glucose. This was further confirmed by pulse labeling with [3H]leucine and chase study. Increased synthesis and secretion of cholesterol in lipoproteins of the VLDL and LDL density range and decreased synthesis and secretion of triglyceride in the VLDL fraction were observed in hepatocytes from sucrose-fed animals compared with those fed glucose. This indicates that the VLDL secreted by hepatocytes from sucrose-fed animals was richer in cholesterol but poorer in triglycerides than from glucose/starch- and glucose-fed animals. These findings also suggest an increase in the synthesis and secretion of apolipoprotein B by hepatocytes on sucrose feeding, indicating an association with an increase in cholesterogenesis.

Animals↗