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R Abelanet

Publications and source records attributed to R Abelanet.

At least 37 records · Page 2Linked to original sources
PubMed1982

[Congenital mesoblastic nephroma. Study of five cases and review of the literature (author's transl)].

Mesoblastic nephroma (individualized by Bolande in 1967) is a congenital renal tumor sometimes locally and regionally aggressive but never giving metastases, in contrast with nephroblastoma. It almost always occurs in the newborn. Therefore, every renal tumor discovered before twelve months must evoke mesoblastic nephroma. No preoperative adjuvant treatment must be used in infants under six months old. Considering five personal observations and review of literature, the authors expose the main etiologic and clinical characteristics of the disease, the gross and microscopic features which allow its diagnosis and the histogenetic theories of this curious lesion, probably border-line between neoplasias and dysplasias of renal parenchyma.

Child, Preschool↗
PubMed1982

[Blood group ABO (H) cell surface antigens in bladder tumours invading the chorion. Prognostic value of their determination by immunofluorescence. Retrospective study of one hundred and twenty-five cases].

The authors have studied 125 stage A bladder tumours with a follow-up period of at least 5 years. The ABH cell surface antigens were collected by a double-layer immunofluorescence technique which has already been described. All the cross sections were read by the same pathologist who knew nothing about the clinical developments. The results were divided into 3 groups : (I) all the tumour cells had retained their surface antigens. (II) Only some cells had retained surface antigens. (III) All cells were negative. Study of the development of the 3 groups shows that : in group I, all the patients (11) are alive 5 years later, and only one has presented with a lesion evolving towards infiltration. In group II (32 patients), only 38 p. cent of the patients are still living 5 years later, and 65 p. cent developed towards muscular infiltration. In group III (77 patients), 27 p. cent are alive after 5 years and 80 p. cent have developed towards muscular infiltration. Homogeneous retention of the surface antigens would therefore seem to be a favourable factor in the prognosis, even in the case of a tumour which has already infiltrated the chorion. The significance of the loss of surface antigens is less clear-cut, but is on the whole adverse. The significance would, however, probably be enhanced by study of the mucosa distal from the lesion, and by marking the substances which determine the blood groups.

ABO Blood-Group System↗
PubMed1982

[Spironolactone bodies. Light and electron microscope study apropos of 4 cases of adrenal adenomas with primary hyperaldosteronism].

So-called Spironolactone bodies are reported in four adrenal cortical adenomas that were removed from patients with primary hyperaldosteronism, treated preoperatively with spironolactone. Their morphology is described optically : these round acidophilic cytoplasmic bodies have a laminated appearance that ranges in size from 2 to 20 mu in diameter. Electron microscopy of the zona glomerulosa non adenomatous cells and of adenomatous cells of glomerular type reveals numerous membranes arranged concentrically around a central core. Connections between the endoplasmic reticulum and mitochondria in the cytoplasm of the cell and lining layers of the body are described and analysed. The authors attempt to explain the formation and the increase of the bodies. Correlations appear between the number of spironolactone bodies and duration of administration of spironolactone and total drug dosage. The results are discussed with those of the literature.

Adenoma↗
PubMed1981

[Tubular filamentous intranuclear inclusions on multinucleated cells of bone giant cell tumors].

Electron microscopy revealed tubular filamentous inclusions within nuclei of giant cells in 22 per cent of 31 cases of genuine giant cell tumours of bone. These inclusions are, both on biopsy and on culture, similar to those of osteoclasts of Paget's disease but less constant, less numerous and mainly intranuclear. Controls by the study of giant multinucleated cells from osseous and extra osseous lesions were negative.

Bone Neoplasms↗
PubMed1981

[Acute chondrolysis following slipped capital femoral epiphysis. A study of 41 cases (author's transl)].

The authors have seen 41 instances of chondrolysis following slipped capital femoral epiphyses. Most of the cases were followed-up for more than five years. The main clinical features are reviewed. There is joint stiffness and generalised narrowing of the joint space during the year following the initial lesion. The evolution of the lesion is unpredictable. A number of possible radiological changes may develop including renewal of the joint space, modifications in the femoral head with a tendency towards protrusio, and osteophyte formation at the lateral margins of the acetabulum. In five cases a biopsy was performed which showed a non-specific dystrophy of the acetabular and femoral cartilage, with sub-chondral bony change different from that found in epiphyseal necrosis. The synovium did not show inflammatory change. The treatment should not be surgical at an early stage but the effectiveness of traction was uncertain. Later, corrective osteotomies may be indicated. Definitive surgical procedures such as arthrodesis or arthroplasty should not be made early because late clinical recovery has been noted. Cup arthroplasties gave deceptive results. The etiology of this disease is discussed.

Adolescent↗
PubMed1981

[Morphological study of a bone tumor. I. Macroscopic, radiographic and cytological aspects (author's transl)].

Pitfalls in histological studies of bone tumor are mostly due to inadequate macroscopic procedures and lack of precise radiological data. Simple technical steps are suggested, including methods of studying resection or amputation specimens, radiographs of tumoral sections, and procedures for obtaining good quality cytological images, particularly useful for the analysis of some types of bone tumors.

Bone Neoplasms↗
PubMed1981

[Calcifications of the mitral valve ring. A clinico-pathological study of 14 cases (author's transl)].

This study of 14 cases, found in 130 autopsies of people died in a Department of Cardio-vascular diseases, emphasizes the frequency of this lesion (10 p. 100) often ignored. Elderly people over 75 years are affected and twice more female than male. Grossly, this abnormality, responsible of a constant mitral insufficiency, is in the posterior cusp attachment at the junction with the ventricular wall. The atrial surface and the line of cusp apposition, commissures and chordae are respected. The main lesions associated with it are left ventricular hypertrophy, coronary and systemic atherosclerosis and most often aortic degenerative calcification, described by Monckeberg, in 50 p. 100 cases. Microscopically, calcifications are surrounded by fibrosis with non specific moderate inflammatory changes. Clinically mitral ring calcification must be searched in case of conduction disturbances of systolic murmurs by left anterior oblique radiography and above all by echocardiography. Except conduction disturbances, complications are infrequent and only seen in advanced lesions. No abnormality of calcium or lipid metabolisms is noted. In agreement with other studies, this one emphasizes the usefulness of echocardiographic diagnosis and the necessity to separate this geriatric entity from advanced post rheumatoid type lesions.

Aged↗
PubMed1980

Fabry's disease.

Explore the source record for details and available documents.

Biopsy↗
PubMed1980

[Configuration and position of centrioles in mono- and multinuclear cells of giant cell tumors of the long bones].

In multinuclear cells of giant cell tumours of long bones studied in biopsies and histiotypic cultures the centrioles were found to be grouped at a distance from the nuclei, forming a giant centrosphere made of diplosomes in equal number to that of the nuclei. This arrangement renders the possibility of new mitotic activity highly unlikely. By contrast, close contacts between multinuclear cells and stromal cells together with the collapse of membranes between cells in contact and the centriolar arrangement represent arguments in favour of genesis by fusion from mononuclear cells of stromal type, in common with many polykaryons. The multinuclear cells of these tumours would appear to represent only the final stage in the evolution of certain mononuclear cells.

Bone Neoplasms↗
PubMed1980

[Pulmonary alveolar microlithiasis. One case (in a child) with ultrastructural analysis and micro-probe analysis (author's transl)].

Authors report on case of pulmonary alveolar microlithiasis with typical chest X-ray, in a six years old boy (without other case of microlithiasis in his family). Pulmonar biopsy shows numerous heavily mineralised microliths in alveolar lumens. Elementary chemical analysis of the microliths (by micro-probe or "ionic" analysis) detects calcium, phosphorus, potassium, sodium, magnesium and carbon, without any exogenous metal. Study (of decalcified tissue) with electronic microscope shows the substrate of mineralisation to ber made of amorphous, non fibrillar, material. In the center of some microliths, membranous structures (possible of cellular origin) were seen. By histochemical study this substrate seems to be a mucoproteic complex with non-sulfated acid polysaccharide component. Histogenesis of such microliths is therefore discussed.

Calcinosis↗