Biomedical subjects

R A Whaley

Publications and source records attributed to R A Whaley.

24 records · Page 2Linked to original sources

PubMed1977

Intracanalicular meningioma with normal tomography. Case report.

A middle-aged woman presented with the typical symptoms and signs of a compressive optic nerve lesion. Plain skull films, tomography of the optic canals, and selective angiography with magnification and subtraction were normal. Computerized transaxial tomography clearly showed the tumor, which was a meningioma of the optic nerve sheath. At surgery the tumor was found within the optic canal with intracranial and orbital extensions. It was strictly intradural and did not involve the surrounding bone at any point. This case documents the fact that an intracanalicular meningioma may be associated with normal tomograms of the optic canal.

Adult↗

PubMed1976

Solitary lytic lesion of the skull.

Thyroid carcinoma metastatic to the calvaria may result in a lytic, well-circumscribed lesion the appearance of which necessitates differential consideration of lytic lesions of the skull. The merits of angiography in the study of such lesions are noted. Even in young persons, the possibility of metastasis presenting as a solitary lytic defect in the skull must be kept in mind.

Adult↗

PubMedDate not supplied

Gadolinium-DTPA enhancement of lung radiation fibrosis.

Gadolinium-diethylenetriamine pentaacetic acid (DTPA) enhancement of radiation-induced apical pulmonary fibrosis was observed in two patients previously treated for breast cancer. In one case the fibrosis was biopsied twice, with no change in its CT appearance over 3 years. Gadolinium-DTPA may enhance benign apical fibrosis after radiation therapy and should not, in and of itself, be used as evidence of recurrent malignancy.

Adult↗

PubMedDate not supplied

Traumatic dissection of the internal carotid artery treated by ECIC anastomosis.

A patient with traumatic dissection of the left internal carotid artery (ICA) was treated by extracranial-intracranial (ECIC) anastomosis. Anastomosis was performed because the near total occlusion of the left ICA was associated with a cerebral transient ischemic attack. At surgery, an embolus was found in a cortical branch of the middle cerebral artery and was removed at the time of the ECIC. Traumatic dissection of the ICA is briefly reviewed.

Adult↗

PubMedDate not supplied

Cerebrospinal fluid analysis in human immunodeficiency virus infection.

Cerebrospinal fluid (CSF) analytes were evaluated in 59 human immunodeficiency virus (HIV+) individuals to assess neurological involvement. Glucose, total protein, cell counts, p24 antigen, CSF: serum albumin/IgG ratios, and oligoclonal bands were measured. Eighty percent of samples showed abnormalities in one or more analyte. In some patients samples, these abnormalities could mimic those of secondary opportunistic infection when none was present. The presence of oligoclonal banding in CSF (31 percent) and disturbances in CSF: serum albumin/IgG ratio (30 percent) were related to decreases in serum CD4+ lymphocytes. Disturbances in CSF: Serum albumin/IgG ratio were also related to severity of non-neurological HIV disease staging. Cerebrospinal fluid oligoclonal bands were distinct from that found in serum in the same subjects. Since immune complexes between immunoglobulins and enzymes are observed in these same patients, these oligoclonal bands may result in artifactually elevated enzyme results secondary to decreased clearance leading to erroneous clinical decisions. There was no significant relationship between any abnormalities and the presence of neurologic disease as established by a wide variety of other studies. It is important to recognize the limits of CSF interpretation in this patient group.

AIDS-Related Complex↗

PubMedDate not supplied

CT recognition of subcortical hematomas.

Subcortical hematomas develop in brain trauma and less commonly in hypertensive intracerebral hemorrhage. Six cases are reported that exhibit a spectrum of computed tomographic (CT) findings in this entity. Pathologic correlates in four cases are presented. It is theorized that subcortical hematomas form in trauma secondary to shearing stresses in the brain. Differential movement of gray and white matter may disrupt cortical medullary vessels. Rupture of degenerative vessels at this junction may account for hypertensive hematomas.

Adolescent↗