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Biomedical subjects

R A Tyrrell

Publications and source records attributed to R A Tyrrell.

At least 19 recordsLinked to original sources

Industrial inspection performance depends on both viewing distance and oculomotor characteristics.

The influence of viewing distance and individual differences in the oculomotor resting states (dark vergence and dark focus) on both inspection performance and visual fatigue was investigated by asking 24 college students to perform a visual inspection task for 40 min twice, once with a 20 cm viewing distance and once with a 60 cm viewing distance. During the task participants visually searched enlarged images of contact lenses for six different types of defects. Lens images were presented at a constant visual angle (17.5 degrees) on a CRT. Inspection performance varied significantly across the two viewing distances: participants spent on average more than twice as much time inspecting individual lenses in the near condition (mean = 18.32 s lens(-1)) than in the far condition (mean = 7.25 s lens(-1)). Participants also reported greater visual fatigue in the near condition than in the far condition. At both viewing distances, participants who experienced relatively large inward shifts in dark vergence also tended to be slow inspectors. Neither inspection performance nor measures of fatigue were related to dark focus. These results support existing evidence against the use of near viewing distances and suggest that an oculomotor mechanism links inspection performance and visual fatigue to viewing distance.

Accommodation, Ocular↗

The assured clear distance ahead rule: implications for nighttime traffic safety and the law.

The assured clear distance ahead (ACDA) rule holds the operator of a motor vehicle responsible to avoid collision with any obstacle that might appear in the vehicle's path. Although widely considered a fundamental responsibility of safe driving, the ACDA rule is routinely violated by most drivers under nighttime conditions. This fact does not necessarily imply reckless disregard for public safety, however. Rather the troublesome discrepancy between drivers' behavior and the principles of safe driving may be understood in terms of vehicle operators' lack of awareness of selective losses of visual function that occur in low light. This theoretical perspective holds basic implications both for traffic regulations and for assessment of liability in nighttime road accidents.

Accidents, Traffic↗

Spectral characteristics of heart period variability during cold face stress and shock avoidance in normal subjects.

Spectral analysis of heart period variability was used to examine autonomic cardiac control in several tasks used in experimental and clinical assessments of autonomic nervous system function. Cardiovascular measures were recorded in healthy humans during quiet rest, reaction time shock-avoidance, cold face stress, and combined shock-avoidance/cold face stress. Shock-avoidance was characterized by sympathetic beta-adrenergic dominance, as evidenced by (1) shorter heart periods, (2) less high-frequency spectral power, (3) elevated low-frequency power, (4) increased ratios of low- to high-frequency power, and (5) a steep regression line fitted to the log-log plot of the power spectra. Cold face stress yielded (1) longer heart periods, (2) more high-frequency power, (3) decreased low-frequency spectral power, and (4) a flat regression slope, indicating vagal dominance. Quiet rest appeared as mildly vagal, with less total spectral power, and the combination task elicited a mixed vagal-sympathetic pattern. These results are discussed in the context of (1) the autonomic underpinnings of low-frequency power, (2) the autonomic effects of facial cooling, and (3) the utility of spectral analysis of heart period variability during autonomic challenge tasks for basic research and clinical application.

Adult↗

Relations between individual differences in oculomotor resting states and visual inspection performance.

Individual differences in the oculomotor resting states (dark vergence and dark focus) have previously been linked to subjective and visual consequences of near visual work. The present experiment investigated whether these resting states are related also to performance on a near visual inspection task. Dark vergence and dark focus were measured in 38 students before and after they spent 40 min searching for a target letter among distractor letters on a video display terminal at a distance of 20 cm. Subjects with relatively near dark vergence positions performed the inspection task significantly more quickly than subjects with relatively far dark vergence positions. Also, subjects who showed a relatively large inward shift in dark vergence tended to perform quickly. Inspection performance was not related to individual differences in dark focus. These results extend existing oculomotor theory and suggest that the performance of visual inspectors is maximized when the mismatch between the task distance and their dark vergence posture is minimized.

Accommodation, Ocular↗

Effects of moderate dose alcohol on visual contrast sensitivity for stationary and moving targets.

OBJECTIVE: Contrast sensitivity involves distinguishing threshold luminance differences and is usually assessed using static sine-wave gratings over a range of different spatial frequencies. The purpose of this study was to determine the effects of various levels of acute alcohol intoxication on contrast sensitivity to stationary and moving sine-wave gratings. Moving gratings required the subjects to make pursuit eye movements. A secondary goal was to investigate whether any alcohol-related effects were associated with any measures of intoxication. METHOD: Male volunteers (N = 8) participated in three counterbalanced, double-blind, testing sessions (low alcohol, moderate alcohol and placebo) plus a control session with no beverage. Breath alcohol concentration and two subjective measures of intoxication were measured for each subject. Static and dynamic contrast sensitivity were determined for electronically generated sine-wave gratings that were either stationary or traveled in a circular path with a diameter of 9 cm (3.7 degrees) at 51.7 rpm, thus requiring the subject to make smooth pursuit eye movements. RESULTS: The mean blood alcohol concentration measured in the moderate alcohol condition was 0.043% and in the low alcohol condition 0.011%. Moderate dose alcohol consumption significantly impaired both static and dynamic contrast with a greater effect for moving targets. CONCLUSIONS: Objective and subjective measures of intoxication were unrelated to the alcohol-related losses in contrast sensitivity. Although most states currently prohibit driving with BACs of 0.08-0.10%, the present data indicate reliable visual impairment at approximately half of that level (.44%).

Adult↗

Measuring and predicting the effects of alcohol consumption on contrast sensitivity for stationary and moving gratings.

Contrast sensitivity was measured for 12 healthy young males while sober, after ingestion of an alcohol placebo, and after ingestion of alcohol (95% grain alcohol; mean estimated blood alcohol level = .088%). Observations were made for both stationary gratings and gratings that traveled through a circular path and required pursuit eye movements. The significant alcohol-related reduction in contrast sensitivity was 2.6 times greater for moving (.29-log-unit reduction) than for stationary gratings (.11-log-unit reduction). The loss in contrast sensitivity for the moving gratings of high spatial frequency (12 cpd) was particularly severe (.37 log unit). Estimated blood alcohol level was correlated with the loss in contrast sensitivity for moving gratings (r = .61), but not with the loss for stationary gratings. Estimated blood alcohol level was strongly correlated with the difference between the loss in contrast sensitivity to moving and stationary gratings (r = .75). These results are consistent with reports that alcohol consumption degrades the ability to make pursuit eye movements. Subjects' perceived intoxication level was not a reliable predictor of any index of visual performance.

Adult↗

Life after downsizing: strategies for organizational healing and revitalization.

In the midst of mergers, acquisitions, and restructuring, organizations are often resorting to painful cutbacks and downsizing. People at all levels are getting laid off. In many cases, tightening the belt is squeezing the very life out of the organization. Savings are often counterbalanced by the lack of productivity of a depressed and demoralized workforce. A structured intervention that addresses survivor issues is necessary for healing to occur. The future of the organization may depend on it.

Adaptation, Psychological↗

Autonomic characteristics of nonclinical panic and blood phobia.

Autonomic characteristics of nonclinical panic and blood phobia were compared using spectral analysis of the electrocardiogram (EKG), as well as more conventional cardiovascular measures. The cardiovascular responses of 11 subjects who reported recent occurrence of frequent severe panic attacks, and 10 subjects who reported intense somatic reactions to the sight of blood (including episodes of syncope) were recorded during a variety of laboratory tasks (quiet rest, reaction time/shock avoidance, face immersion, and combined reaction time/face immersion). Results suggest distinct autonomic patterns in the groups. Panickers showed (a) higher heart rate and reduced heart-rate variability (b) aberrant associations among cardiovascular measures, and (c) dominant sympathetic control of heart rate coupled with diminished vagal tone. Blood phobics generally displayed an opposite pattern. The relevance of these findings to the etiology of panic and blood phobia, as well as to biological models of anxiety disorders in general, is discussed.

Adult↗

Evidence for the persistence of visual guidance information.

An earlier study from our laboratory provided initial support for the hypothesis that information facilitating visual guidance persists in the absence of retinal stimulation. The present study supports and extends this hypothesis with three experiments in which visually occluded subjects positioned a point of light at the location of a previously viewed target and also walked in the direction of a previously viewed path. In both tasks, performance was possible following occlusion, and in all cases, performance slowly and significantly decreased with longer durations of occlusion. This decay in performance was gradual and had a "half-life" of greater than 15 sec. Absolute performance was correlated across tasks. The effect of occlusion on absolute error in the localization performance was relatively stable within individuals over a 3-week period. The biological utility of guidance information persistence is discussed along with implications for space constancy, illusions of motion, and problems of disorientation.

Adolescent↗

Age differences in dynamic contrast thresholds.

Contrast thresholds for sinusoidal gratings of 1.5-18 cpd were measured in young (M = 24 years) and older adults (M = 69 years). Thresholds were determined for stationary gratings, and for gratings that traveled along a circular path at 5, 10, and 15 deg/sec. For static gratings, age differences in thresholds were greater for intermediate and higher spatial frequencies. Grating motion increased thresholds for all observers, but older adults exhibited threshold increases at lower target velocities than the young. Age differences in velocity effects were generally greater at intermediate and higher spatial frequencies. Results are discussed in relation to age changes in temporal resolution and smooth pursuit gain.

Adolescent↗

The effects of visual factors and head orientation on postural steadiness in women 55 to 70 years of age.

This study was designed to establish reference data for the effects of head position and visual conditions on the standing posture of healthy women ages 55 to 70. Center of pressure (CoP) data were analyzed using ANOVA models. Total CoP displacement was 45% greater (significant, p less than .05) when the subjects stood with their heads back and their eyes closed, as compared to standing looking straight ahead. Visual surrounds consisting of vertical visual cues resulted in less postural sway (PS) than surrounds made of horizontal visual cues (significant, p less than .05 for anteroposterior CoP range). Experimentally reduced visual acuity resulted in greater PS, while changes in ambient lighting and spatial frequency of visual cues affected PS minimally. These results suggest that a reduction in the height of shelving, and the provision of high-contrast visual cues and vertical geometric patterns are potential intervention strategies to optimize vestibular sensory input and visual orientational cues for the maintenance of stability during stance.

Aged↗

Lateral phoria at distance: contributions of accommodation.

Lateral heterophoria at distance often is cited as an index of tonic vergence, yet recent research has shown that vergence in darkness is more convergent than most measures of phoria. Two experiments were conducted to investigate the possible role of accommodation in this discrepancy. Experiment I compared measures of distance phoria of 19 young adults with measures of vergence and accommodation of the same subjects. Dark vergence was found to be correlated with but significantly more convergent than distance phoria. Hierarchical regression analysis showed that individual measures of phoria were related to subjects' negative accommodation (from the dark focus to the distant target) as well as to dark vergence. Experiment II tested 13 young adults to evaluate three simple models of the influence of accommodation on distance phoria. Distance phoria was predicted best by a model that included the subjects' negative accommodation, accommodative vergence, and dark vergence. These findings support the hypothesis that distance phoria is influenced by accommodation for the fixation target. Dark vergence is a simpler index of tonic vergence.

Accommodation, Ocular↗

Age differences in estimating vehicle velocity.

Automobile accidents among older adults may be related to difficulties in judging the speed of other vehicles. To examine this possibility, 3 groups of observers in the young adult, middle-aged, and older adult age ranges were asked to estimate the velocity of an isolated automobile traveling at 15-50 mph (24-80 kph). Across all age groups, perceived and actual velocity were related by a power function with an exponent of 1.36. Age was significantly and positively correlated with intercepts, but negatively correlated with exponents; that is, older observers showed less sensitivity to changes in actual velocity. Results bear on the issues of ontogenetic changes in accident involvement and sensitivity to motion.

Acceleration↗

The influence of visual factors on fall-related kinematic variables during stair descent by older women.

Despite the documented health hazards associated with stair descent, the mechanisms of falling on stairs remain relatively unexamined. The objectives of this study were to define kinematic variables that could be used to describe foot-stair spatial relationships during the mid-stair phase of stair descent, and to investigate the effects of various visual and environmental conditions on those variables in a group of 36 healthy women between the ages of 55 and 70. Foot clearance and foot placement were measured through high-speed film analysis. Clearance between the foot and the stair during swing phase was small under all visual conditions. Degraded visual acuity had a significant effect on cadence, foot placement, and foot clearance, but visual surround conditions did not. The kinematic variables used in this experiment may be helpful in future studies to assess the results of interventions aimed at reducing the frequency of falls on stairs.

Accidental Falls↗

Bandwidth of the contrast sensitivity function as an index of spatial vision with application to refraction.

The contrast sensitivity function (CSF), although containing more information than traditional measures of acuity, has found difficulty gaining clinical acceptance. The hesitancy of clinicians to adopt the CSF stems, in part, from the fact that it is not as readily interpreted as is acuity. In order to facilitate such interpretation, five indices of spatial vision which are derivable from the CSF were examined in a sample of 287 persons aged 5 to 85 years. All indices were found to be both age-sensitive and strongly related to each other, but bandwidth of the CSF was chosen as a practical index for clinical settings. In a second study, acuity and CSF bandwidth were measured under 0 to +/- 1 D optical blur. It was found that the correction providing best acuity also maximized CSF bandwidth, and that bandwidth was more sensitive to optical blur than was acuity. Results support the assertion that CSF bandwidth is a readily interpreted index of spatial vision that can be measured efficiently within the context of clinical refraction.

Adolescent↗

The relation of vergence effort to reports of visual fatigue following prolonged near work.

Two experiments examined the link between vergence effort and subjective reports of visual fatigue following prolonged near work. In Experiment 1, dark vergence and reports of visual fatigue symptoms associated with computer use were measured in 104 persons. Dark vergence was significantly correlated with four of six symptoms of visual fatigue. In Experiment 2, 16 subjects who exhibited clear "Heuer effects" (systematic gaze-related changes in dark vergence) read from a video display terminal (VDT) at a distance of 20 cm for 60 min under two gaze elevation conditions: 20 deg above and 20 deg below a baseline gaze elevation. This manipulation was designed to vary the amount of vergence effort required to fixate the VDT. Results indicate a positive relation between vergence effort and visual fatigue both within and between subjects, and that prolonged near work leads to decreased vergence accuracy at far distances. Implications for VDT workstation design are discussed.

Adolescent↗

Age differences in Vistech near contrast sensitivity.

Contrast sensitivity was measured at near using the Vistech 6000 Contrast Test System (VCTS) in 287 persons aged 4 to 87 years. Obtained data compared well with those previously reported for the Vistech charts. Results indicate an age-related loss in sensitivity to intermediate and higher spatial frequencies. This is consistent with the age trends observed using other methods for measuring contrast sensitivity functions (CSFs). However, the Vistech charts yield contrast sensitivity values which are lower than those obtained previously with the Nicolet system. These between-method differences are greatest at lower spatial frequencies, and are attributed to the small number of grating cycles in the Vistech charts. The data are used to develop provisional age norms for the Vistech charts which allow the assessment of an individual's performance relative to their age cohort. Recommendations for use and future development of the Vistech charts are also given.

Adolescent↗