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R A Tange

Publications and source records attributed to R A Tange.

At least 19 recordsLinked to original sources
PubMed1992

[Predictive value of high frequency audiometry in otosclerosis].

A study was carried out to evaluate the value of high-frequency audiometry in stapes surgery in cases of otosclerosis. The hearing function was measured pre- and postoperatively by means of conventional and high-frequency audiometry (Demlar 20k). The operative findings of the gradation of otosclerosis were compared with the pre and postoperative audiometrical measurements. The results of this study point out that a clear relation exists between the preoperative high tone audiogram and the gradation of otosclerosis. In conclusion, we state that high-frequency audiometry can predict the state of stapes fixation in otosclerosis and that can be important in stapes surgery.

Audiometry↗
PubMed1991

Ototoxicity monitoring with ultra-high frequency audiometry in peritoneal dialysis patients treated with vancomycin or gentamicin.

Ototoxicity affects the higher frequencies first and extends to the lower frequencies during continuation of the ototoxic treatment. Peritonitis due to continuous ambulatory peritoneal dialysis (CAPD) regularly demands ototoxic antibiotic treatment, e.g. with gentamicin and vancomycin. In this study ultra-high frequency audiometry (10-20 kHz), 'normal' audiometry (0.125-8 kHz) and registration of blood concentrations of the antibiotics were used to assess ototoxic hearing loss during treatment of CAPD patients with peritonitis.

Audiometry↗
PubMed1991

Some historical aspects of the surgical treatment of the infected maxillary sinus.

Sinus surgery probably originates from the time of the New Kingdom of ancient Egypt. Instruments were used to remove the brain through the nose as a part of the mummification process. The interest in the pathology of the maxillary sinus started to rise in the 17th century. Antral trephination for suppuration was the most common maxillary sinus operation in that period. An oro-antral fistula was often created by the extraction of a molar to drain the infected maxillary sinus daily. Later on the anterior wall of the maxillary sinus was opened through the canine fossa and was kept open for irrigation. Caldwell (1893), Scanes Spicer (1894) and later Luc in 1897 closed the canine fossa incision after an intranasal antrostomy and the removal of the infected mucosa. This so-called Caldwell-Luc procedure is still the most commonly used maxillary sinus operation today. After the introduction of the endoscopy in the beginning of this century endonasal surgery has been developed in the last decades into one of the important surgical procedures for maxillary sinus infections today.

Egypt↗
PubMed1990

Progressive fatal dementia (Creutzfeldt-Jakob disease) in a patient who received homograft tissue for tympanic membrane closure.

We report the case history of a 54-year-old man who developed a fatal neurological disorder 4 years after a successful tympanoplasty with homograft pericardium. The final diagnosis of this case was Creutzfeldt-Jakob disease. This infectious spongiform encephalopathy is probably caused by a slow virus that can be transmitted by transplantation materials. The possible accidental transmission of Creutzfeldt-Jacob disease by the use of homograft materials in otologic surgery is discussed.

Cerebral Cortex↗
PubMed1990

Pre- and postoperative high-frequency audiometry in otosclerosis. A study of 53 cases.

A study was carried out to evaluate the results of stapes surgery in 53 cases of otosclerosis. The hearing function was measured pre- and postoperatively by means of conventional and high-frequency audiometry (Demlar 20K). The operative findings of the gradation of otosclerosis were compared with the pre- and postoperative audiometrical measurements. The results of this study point out that a clear relation exists between the preoperative high-tone audiogram and the gradation of otosclerosis. Stapedotomy does not influence the high-frequency threshold postoperatively. In conclusion, high-frequency audiometry can predict the state of stapes fixation in otosclerosis and this can be important in stapes surgery.

Audiometry↗
PubMed1989

An experimental study of vancomycin-induced cochlear damage.

Vancomycin has been successfully used clinically for many years. Although early reports found ototoxicity to be a side effect of this antibiotic, later studies could not confirm this. For this reason we have started an experimental study in an animal model on the ototoxic effects of vancomycin. We now report the results of this study. Fourteen healthy Mongolian gerbils were treated with intraperitoneal injections of vancomycin (80 mg/kg per day) for a 2-week period. Before and after treatment each animal's hearing was evaluated by evoked response audiometry. Post mortem the cochleae were investigated by scanning electron microscopy in Amsterdam and by microdissection with surface preparations (hair cell counting) in Stockholm. The results of this study show that there is no clear evidence for the existence of ototoxicity due to vancomycin in this dosage.

Animals↗
PubMed1989

Role of high-frequency audiometry in the early detection of ototoxicity. II. Clinical Aspects.

As a supplement to a previous paper [Dreschler et al.: Audiology 1985; 24:387-395] high-frequency (HF) audiometry was applied to compare the ototoxic effects of two different drug administration protocols for cis-platinum (CDDP). In both subgroups, HF audiometry considerably enhanced the early detection of ototoxicity. Marked differences between treatments have been established both in the pattern of onset of the damage and in the relation between dose and damage severity. For subjects treated with platinum derivatives, the thresholds at 12 and 14 kHz prove to be especially important. The results suggest that for these subjects the measurement of only a single frequency may be considered: with a minimum of effort, most of the increased sensitivity for a complete HF audiogram can be obtained. Finally, the relation between threshold deteriorations above 8 kHz and threshold deteriorations in the conventional range of audiometric frequencies has been investigated.

Adult↗
PubMed1987

Otorhinolaryngological findings in AIDS patients: a study of 63 cases.

Patients with acquired immunodeficiency syndrome (AIDS) frequently show signs and symptoms involving the head and neck. We reviewed the clinical histories of 63 cases with AIDS, with patients treated from 1982 to December 1985, in our hospital. Findings referable to the head and neck were seen in 43 patients. Comparison with a previous study in San Francisco revealed remarkable differences. We found otolaryngological manifestations in 68% of the patients in contrast to 41% in this latter study. We saw more rapidly increasing neck masses, a greater incidence of shortness of breath and chronic cough, and an increased occurrence of candidiasis. The number of cases with Kaposi's sarcoma lesions was equal in both studies.

Acquired Immunodeficiency Syndrome↗
PubMed1987

Pathological findings in the human auditory system following long-standing gentamicin ototoxicity.

The clinical, audiovestibular and histopathological findings in a patient who suffered from a long-standing gentamicin-induced deafness are reported. In both temporal bones, the organ of Corti was completely absent, with only a few nerve fibres remaining in the apical part of the cochlea. Regenerative ingrowth of nerve fibers into the area of the degenerative organ of Corti was present apically in both ears. The stria vascularis exhibited considerable degeneration in all turns and loss of microvasculature was found in the basilar membrane. The spiral ganglion cells, the cochlear nerve and the central auditory pathways and nuclei appeared to be unaffected.

Adult↗
PubMed1987

Vasculature of the crista ampullaris of the rat as seen in microcorrosion casts.

A scanning electron microscope study of corrosion cast preparations of the vessels of the crista ampullaris was carried out in adult rats. This method shows the microvasculature of the cristae in the three-dimensional model. As a result of this technique we have been able to demonstrate on microscopical level a particular microvasculature in the septum cruciatum of the crista in rat.

Animals↗
PubMed1987

An abnormality in the human cochlear vasculature in a case of cis-platinum ototoxicity.

The histopathological findings of a study of a human temporal bone are reported. The subject of this study was treated with cis-platinum in combination with bleomycin. High-frequency audiometry was performed pre- and post treatment. Microdissection for surface preparation was carried out after death. An unusual blood vessel in the cochlea was found. The possible cause of this vascular abnormality in the human cochlea is discussed.

Abnormalities, Drug-Induced↗
PubMed1986

[Furosemide].

Explore the source record for details and available documents.

Ear, Middle↗
PubMed1986

The vascular anatomy of the spiral lamina and the spiral limbus in the adult rat. A scanning electron microscope study of corrosion cast preparations.

A scanning electron microscope (SEM) study of corrosion cast preparations of the vessels of the spiral lamina and the spiral limbus was carried out in adult rats. This method confirms present knowledge of the modiolar vascularization and also shows its distribution in a three-dimensional model. As a result of this technique we have been able to demonstrate the modiolar vascular supply of the organ of Corti at different levels.

Animals↗
PubMed1986

The vasculature of the external wall of the gerbil's inner ear.

This paper reports the results of a scanning electron microscopy (SEM) study of the vessels in the cochlea of the Mongolian gerbil. Using the microcorrosion technique and SEM we were able to obtain an overall picture of the capillary beds in the cochlea of the gerbil. The vasculature of the inner ear of the gerbil was found to differ from Wistar rats. The different vascular anatomy in comparison with the Wistar rat is discussed.

Animals↗
PubMed1986

Cranial hyperostosis and hearing loss (a new syndrome?).

We present two patients, mother and daughter, with a skeletal disorder of the skull, hearing loss and in one of them recurrent facial paralysis. In one patient middle ear exploration was performed. The malleus and incus were found to be fixed in the epitympanum. The differential diagnosis is discussed. We reviewed all known hereditary conditions with hearing loss and musculoskeletal disease but we could not accept any of these diagnoses for our patients.

Adult↗
PubMed1986

Localized aspergillosis involving the nose and paranasal sinuses.

Two patients with non-invasive aspergillosis of the paranasal sinuses are reported. One patient had this disease in the maxillary sinus while the other had it in the ethmoid and sphenoid sinus. Caldwell-Luc and a transnasal ethmoidectomy operation were performed. The treatment and prognosis of this rare nasal infection are discussed.

Adult↗