[The use of infrared radiation in treating a nonhealing recurrent and peptic ulcer].
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Biomedical subjects
Publications and source records attributed to R A Sadykov.
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The authors have established in vitro, that helium-neon (HN) laser rays at the therapeutic doses had no bactericidal effect. Bactericidal effect of the rays of an ultraviolet (UV) laser is manifested in exposure for 5 min (output power of 3 mW, pulse frequency of 100 Hz, diameter of the irradiated area of 3 mm). In the clinic, a combined method with the use of HN-laser with radiant power of 20 J/cm2 and UV laser with radiant power of 7 J/cm2 was employed. Duration of treatment of purulent-inflammatory diseases reduced 2-5-fold as compared with that in use of conventional methods of treatment.
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In patients with an ulcer of the stomach and duodenum at the immediate postoperative period in the complex of treatment, the low intensity laser irradiation of the anastomosis (after gastric resection) and ulcer (after the organ-preserving operations) according to the developed method by means of the modified LG-75 apparatus was used. The use of a helium-neon laser contributed to development of the severe form of anastomositis and subsequent gastrostasis. In study of gastric secretion, no considerable changes in acid formation were revealed.
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The process of potassium benzylpenicillin vacuum drying was investigated. The kinetics of the process showed that a larger period of the drying process was needed for eliminating bound moisture. The influence of the angular velocity of the drier drum rotation on drying duration was studied in a short-term contact model. It was shown that intensity of drying increased with increasing velocity of the drum rotation. Experimental trials confirmed the conclusion and revealed adequacy of the relationship between the drying time and dispersion intensity in the short-term contact model. A qualitative dependence of the coefficient of convective heat exchange between the heating surface and the product on the angular velocity of the drier drum rotation was constructed.
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Organ-preserving operations on the stomach when combined with vagotomy were found to reduce the acid formation in the stomach which facilitates healing of the duodenal ulcer.
The pyloric glands and muciferous superficial cells of the pyloric mucosal membrane have been studied in 62 patients with complicated forms of duodenal ulcer--preoperatively, 2--4 weeks, 6--12 months following truncal vagotomy with drainaged stomach. The light transmission and scanning electron microscopy and stereometry, were used as well as the determination of mucosal production and intragastric pHmetry. It is shown that vagotomy leads to a decrease of inflammatory changes without an essential influence on the pyloric gland size. Ultrastructure of muciferous cells gives evidence of their significant possibilities for mucus production, although the production of gastric mucosal components decreases postoperatively. Apart from this essential decrease of the main and parietal cell size and their secretory activity was noted. This provides an adequate level of acid-neutralizing gastric function following vagotomy.
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The use of quantitative analysis (point system) suggests that informativeness of a complex of tests of radioactive iodine absorption by the thyroid and radioimmunoassay of hormones is conclusive. It is recommended that a staged approach (primary application of the available tests) be used in the diagnosis of thyroid dysfunction.
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Gastric contents was examined in 49 patients with duodenal bulb ulcers. Helicobacter pylori were isolated in 83.7% of cases. H. pylori density was found to be 10(3)-10(5) microbial cells per ml. Bacterioscopic studies with gram staining helped detect H. pylori in 79.6% of cases, cultural method revealed the bacteria in 63.3%, and urease test in 4.1% of cases. Poor efficacy of urease test is explained by its poor sensitivity (10(6) microbial cells per ml or higher). The authors analyze the frequency of H. pylori isolation in relation to the month of the examination and gastric contents coloring.