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Biomedical subjects

R A JOSKE

Publications and source records attributed to R A JOSKE.

At least 19 recordsLinked to original sources
PubMed1964

THE 5 G. D-XYLOSE ABSORPTION TEST.

The 5 g. d-xylose absorption test has been studied in 50 normal subjects. The five-hour urinary xylose content was 1.75 +/- 0.43 g. Xylose absorption was more rapid and more complete with the 5 g. than with the 25 g. test. Comparative studies showed the results of the two tests to be significantly related, but the 5 g. test was a less sensitive indicator of malabsorption than the 25 g. test. The 25 g. test is considered the more suitable for routine use in temperate climates.

Absorption↗
PubMed1963

THE VITAMIN B12 CONTENT OF HUMAN LIVER TISSUE OBTAINED BY ASPIRATION BIOPSY.

It is possible to estimate the vitamin B12 content of liver specimens obtained by needle biopsy. The liver B12 content is not related to the serum levels of vitamin B12, bilirubin, alkaline phosphatase, glutamic-oxaloacetic transaminase, or albumin. It is reduced in a number of pathological conditions of the liver and the reasons for this are discussed, as also are the factors determining the content of B12 in the normal liver.

Aspartate Aminotransferases↗
PubMed1960

Folic acid and other absorption tests in lymphosarcoma, chronic lymphocytic leukaemia, and some related conditions.

An improved folic acid absorption test is described in detail. Using the folic acid and other absorption tests, a study of intestinal function has been made in eight patients with lymphosarcoma, eight with chronic lymphocytic leukaemia, two with Hodgkin's disease, and one each with reticulum cell sarcoma, Whipple's disease, and macroglobulinaemia. It was found that laboratory evidence of intestinal malabsorption was extremely common in patients with this group of diseases. The folic acid absorption test was the most sensitive single index of malabsorption of the tests used in this study. Correlation between the different absorption tests was poor, and there does not appear to be a characteristic biochemical profile of intestinal function in these patients.

Animals↗