Hydrazine-deproteinated bone mineral. Physical and chemical properties.
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to R A Harper.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
A sample preparation technique was developed for observing the orientation of collagen fibers in the lamellas of human osteonic bone by means of scanning electron microscopy. Scanning electron micrographs of these fiber orientations are given in the text.
Explore the source record for details and available documents.
Alveolar macrophages were removed from male F-344 rats by bronchoalveolar lavage and maintained in vitro for 14 days. Over this period the macrophages remained viable as judged by propidium iodide exclusion, lysosomal uptake of acridine orange, and phagocytosis of 1.75-microns latex beads. After 7 and 14 days of culture the cells contained lipid droplets. The macrophages were shown to ingest and dissolve monodisperse 57Co3O4 particles, which were relatively insoluble in extracellular medium. The fraction of 57Co3O4 dissolved intracellularly was determined at intervals during the culture period. The mean dissolution rate (+/- SEM) was 0.36 +/- 0.02% per day for the F-344 rat. This was lower than 1.4 +/- 0.05% per day estimated by Kreyling in macrophages from the beagle dog. The significance of this difference is discussed.