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Biomedical subjects

R A Goldenberg

Publications and source records attributed to R A Goldenberg.

27 records · Page 2Linked to original sources

Management of Meniere's disease. Surgery may help if medication fails.

Meniere's disease is the classic triad of fluctuating hearing loss, episodic vertigo, and severe tinnitus. It usually occurs unilaterally, although about 15% to 20% of patients may have bilateral disease. The disease involves a series of acute exacerbations followed by a period of remission; it progresses until the ear has essentially "burned itself out," causing symptoms to subside. Treatment of Meniere's disease should be tailored to the severity of symptoms and the patient's life-style. Initial treatment involves conservative medical management and psychologic support. If this fails, endolymphatic shunt surgery is effective in alleviating symptom in the majority of patients.

Ear, Inner↗

Endolymphatic mastoid shunt for treatment of Meniere's disease: a five year study.

The endolymphatic mastoid shunt seems to be an effective treatment for those patients whose Meniere's disease is refractory to medical and/or supportive treatment. This series is composed of 48 patients who were followed for up to 5 years postoperatively, with 1 year being the minimum follow-up period; 81% of these patients obtained a satisfactory relief of their vertigo. The morbidity of the procedure is low with no severe or total hearing loss reported in this series. Surgery should not be recommended until the symptoms have caused severe incapacitation; however, this delay must be tempered by the desire to operate while the hearing is still fluctuating. One of the most important factors in the surgical success may be the exact identification and exposure of the sac at the time of surgery, regardless of the specific shunt technique used. Shorter duration of symptoms and lack of fluctuant hearing loss may be preoperative factors which predict a less satisfactory surgical result. While the endolymphatic shunt procedure is effective in the majority of cases, the patient should be prepared for a secondary procedure if necessary.

Adult↗

Pleomorphic adenoma manifesting as aural polyp. Report of a case.

We report the sixth known case of a pleomorphic adenoma of the external auditory canal. It manifested as an aural polyp, and the diagnosis was made only after microscopic pathologic examination. Complete removal was accomplished after a total parotidectomy (with preservation of the facial nerve) provided access to the parapharyngeal space surrounding the internal carotid artery, where it is postulated that the tumor originated. A thorough knowledge of the developmental anatomy of this area greatly enhances operative success.

Adult↗

Ossiculoplasty: a refined method to prepare homograft ossicles.

The purpose of this paper is to present a technique of preparing a homograft ossicular prosthesis in the most efficient and precise manner for use in ossicular reconstruction. While there are other techniques of reconstruction, this technique will benefit those surgeons who utilize homograft ossicles for hearing reconstruction. There are two major advantages of this technique. First, operating time is decreased because of preparations of the prostheses in advance. Second, the prostheses may be more precisely shaped than by other methods. The technique of preparation is not difficult and may be done by ancillary surgical personnel readily trained in this simple method.

Ear Ossicles↗

Averaged evoked potentials in cats with lesions of auditory pathway.

Averaged evoked activity was recorded from needle electrodes placed at the vertex of the calvaria and adjacent to each bulla in anesthetized cats in response to click stimuli. The portion of the response from 0 to 10 msec was analyzed. Activity during the first 3 msec was greatly reduced on the side ipsilateral to a lesion involving destruction of the cochlea or section of the eighth nerve and its blood vessels. Activity after 4 msec was greatly reduced on the side ipsilateral to destruction of the cochlear nuclei. No effect was found with destruction of both inferior colliculi. The bulla-vertex evoked responses were also compared to those recorded from the round window. The results support the premise that change in the wave-form of the early evoked potential can be used to determine site of loss of acoustic information along the auditory pathway.

Acoustic Stimulation↗