Functional alterations in GABAergic inhibition during activity.
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Biomedical subjects
Publications and source records attributed to R A Deisz.
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The effect of penicillin on the evoked IPSP was investigated in the isolated crayfish stretch receptor. The IPSP driving force (IPSP reversal potential minus membrane potential) was reduced in a dose-dependent fashion but, when necessary correction was made for the decrease in resting membrane conductance, the synaptic conductance was only slightly reduced. The possibility that a penicillin-induced intracellular acidification was responsible for the decrease in IPSP driving force is considered.
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Explore the source record for details and available documents.
Explore the source record for details and available documents.