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Biomedical subjects

Paweł Strek

Publications and source records attributed to Paweł Strek.

10 recordsLinked to original sources

Fatty tissue within the maxillary sinus: a rare finding.

BACKGROUND: We report a rare case of fatty tissue within the maxillary sinus in a 21-year-old woman, with a history of several previous punctures of the maxillary sinus. CASE PRESENTATION: Clinical data of the patient was analysed retrospectively. The patient presented with symptoms of left-sided chronic maxillary sinusitis and had undergone several punctures of the left maxillary sinus 18 months earlier. Subsequent to one of the procedures an acute pain in the left orbit lasting a couple of days was noted. Left endoscopic transnasal antrotomy was performed. The maxillary sinus was filled with polypous, chronically inflamed mucous membrane. Upon its removal, the maxillary roof was identified as drawn downwards and covered with normal mucous membrane. Upon dissection of the membrane, adipose tissue filling the zygomatic recess of the sinus was identified and subsequently removed. The maxillary roof was unchanged. Histopathologic examination confirmed the material to be adipose tissue. No short or long term sequelae occurred. CONCLUSION: Adipose tissue can be found in the maxillary sinus most commonly when penetrating from surrounding locations. It is our hypothesis that in the reported patient it penetrated from the orbit to the maxillary sinus following puncture. It seems that a hole in the maxillary sinus roof, about 1 mm in diameter, caused by the needle, may have been a portal of entry for the adipose tissue into the maxillary sinus. The discussed case suggests particular care be taken in performing puncture of the maxillary sinus.

Adipose Tissue↗

[Olfactory neuroblastoma removed under endoscopic guidance].

INTRODUCTION: Olfactory neuroblastoma is a rare tumour associated with high rates of recurrence and mortality. Treatment includes surgery, radiotherapy, chemotherapy, or a combination. The ideal treatment modality has yet to be determined. MATERIAL AND METHODS: 46-years old male underwent bilateral endoscopic ethmoidectomy due to chronic sinusitis. During surgery, a 5 mm in diameter tumour was identified in the left superior nasal meatus. On histopathological examination the diagnosis of esthesioneuroblastoma was established and confirmed by immunohistochemistry. The tumour was classified according to Kadish as stage A, according to Biller as T1. MR scans performed two months later disclosed pathological tissues in the left ethmoid region. RESULTS: Multiple biopsies taken on subsequent frontosphenoethmoidectomy did not contain tumour cells. The patient declined radiotherapy. He has been asymptomatic over the 12 monthsí follow-up period. CONCLUSIONS: The exclusively surgical treatment proved effective due to early stage of the tumour and no evidence of infiltration of the frontal skull base. This strategy, however, requires frequent follow-up visits.

Endoscopy↗

[Correlation between computed tomography and microbiological results in chronic sinusitis].

This article presents the observed correlation between the advancement of inflammatory lesions in paranasal sinuses found on computed tomography and microbiological specimen results in chronic sinusitis. The examined study group consisted of 28 patients, aged 19-59 years, in whom endoscopic sinus surgery was performed. In each patient prior to planned surgery a sinus CT scan was performed the result of which was scored using the Lund-Mackay scale, bacteriological and mycological examinations of nasal mucous secretion were also performed. In the study group a positive correlation between the CT score point sum and the number of pathogen species (regression test: r = 0.46; p = 0.0141) was found. With each additional pathogen species found the CT grading rose by 2.3 points. We also found that in patients with positive bacterial culture the average CT score rose by 4.4 (ANOVA: F(1,23)= 3.69; p = 0.0333). However no rise was found in the case of fungi and no interaction between bacteria and fungi was found. In cases of advanced sinusitis where a high CT lesion score of is found antimicrobial therapy based on exact microbiological diagnostics should be given in the perioperative period.

Adult↗

[Self-assessment of the effect of dysphagia on the quality of life in patients after partial laryngectomy for cancer initially located in the supraglottic area].

Dysphagia is frequent in patients after partial laryngectomy for cancer initially located in the supraglottic area. To ensure the best quality of life, establishing how the patient feels after treatment is necessary. Therefore, a self-administered questionnaire was designed to evaluate the dysphagia. 95 patients (75 male and 20 women) who were operated in ENT Department CMUJ between 1998-2004 participated in this study. The MDADI questionnaire in the Polish version was used. The subjective evaluation by the patient of dysphagia is directly related to the size of the tumor and the extent of the partial laryngectomy treatment. Patients, whose tumor was located in supraglottic-glottic area, had subtotal laryngectomy m. Miodoński. Their quality of life was significantly worse due to dysphagia than those with tumors located only in the supraglottic area. Swallowing dysfunctionality was significantly greater after the resection of the hyoid bone. Reconstruction of the base of a tongue by a graft of angiopedunculated submandibular gland diminished the difficulties in swallowing. Moreover, the longer the period after treatment, the higher the quality of life becomes because of the improvement in the swallowing functionality.

Adult↗

[Functional assessment of posterior cordotomy in patients with bilateral vocal fold paralysis].

UNLABELLED: Surgical treatment of bilateral vocal fold paralysis must be undertaken if such a condition lasts 6-12 months or longer and causes dyspnoea. The purpose of the procedures is to assure proper airflow through the glottis and to preserve good voice and unimpaired swallowing. Modern endoscopic surgery of the glottis is performed with CO2 laser. The following paper presents results of laser posterior cordotomy performed in 17 patients aged 19-73 years suffering from bilateral vocal fold paralysis. RESULTS AND CONCLUSIONS: In 7 patients the range of vocal fold resection had to be expanded. 3 individuals developed post-operative granulation in subglottal region. Spirometry and electroglottography were performed before and after the operation to assess the patients' laryngeal functions: respiration and voice quality. The results indicate that laser cordectomy was effective in the discussed group of patients.

Adult↗

[Preliminary study of the frequency of micronuclei in buccal mucosa cells sampled from patients with laryngeal tumors].

The examination of frequency of micronuclei was carried out on two groups of patients with tumors of upper respiratory tract: cancer of larynx (36 individuals) and polyps of larynx (13 persons). Groups of habitants from Katowice, Czestochowa and Nowy Sacz (cities with the different level of air pollution) and separately group of smokers, were considered as the control. It was observed that high frequency of micronuclei in cell of buccal mucosa from individuals exposed on mutagenic substances from the air and cigarette smoke could be a marker of higher risk of carcinogenesis.

Air Pollution↗

[Nonallergic rhinitis with eosinophilia syndrome: state of knowledge].

The aim of our article was to present the actual state of knowledge of the non-allergic rhinitis with eosinophilia syndrome (NARES). NARES is characterized by perennial rhinitis and nasal eosinophilia in the absence of allergy in patient's history, negative skin tests and normal IgE. This syndrome was described 20 years ago, but studies on it are scarce. NARES is more frequent in females at mean age. Family history is positive in part of cases. The clinical symptoms are sneezing, watery rhinorrhea, nasal obturation and nasal itching. The precipitating factors are often nonspecific irritants, weather changes or strong odors. It is not sure whether NARES is a form of a vasomotor rhinitis or a first stage of aspirin triad. A presence of bronchial hyperactivity was detected in part of patients with NARES. The crucial feature of the non-allergic rhinitis with eosinophilia syndrome is nasal eosinophilia. Its diagnosing value, mechanisms and different methods of its measurement and differential diagnosis are discussed. The treatment of NARES with nasal steroids is highly effective. The patients may also benefit from the treatment with the oral antihistamines.

Bronchial Hyperreactivity↗

[Our experience in treatment of patients with inverted papilloma of lateral nasal wall].

Inverted papilloma is a benign neoplasm of uncertain etiology arising from the lateral nasal wall and middle meatus. The tumour is considered locally aggressive. In selected cases inverted papilloma can be associated with squamous cell carcinoma. Computed tomography and magnetic resonance imaging are widely used for diagnosis and preoperative workup to evaluate the degree of sinus involvement. Its tendency to invade adjacent paranasal structures and high recurrence rate causes controversy as to the optimal method of surgical removal. During the past decade, endoscopic surgical approaches have become accepted as standard of care in case of inverted papilloma. Continually increasing skill with the use of the endoscopes and a better understanding of the anatomy of the region have allowed surgeons to extend the applications of sinus endoscopic surgery. The following paper reports clinical outcome of treatment of 20 patients with inverted papilloma of the lateral nasal wall treated in ENT University Department in Kraków, provides review of current literature concerning the subject and discusses indications and contraindications of this method of treatment in comparison with traditional extranasal approaches in order to search for the optimal philosophy of sinus surgery for inverted papilloma.

Adult↗

[Language tests in electroglottography].

An Electroglottograph (Fourcin Laryngograph Processor) was used to determine, whether there was a significant difference in degree of Irregularity in vocal fold vibration (% Irregularity) or Contact Quotient (Qx) in the vocal fold vibratory cycle (Lx) between different phonatory tasks and between men and women. The most recent software package, 'Speech Studio', was used to analyse the data. The subjects were 24 healthy subjects, 16 females and 8 males, aged from 22 to 71. The tasks consisted of sustained vowels: a, o, u, short words: Ala, Ola, Ula and a short phrase in Polish, spoken at comfortable pitch and volume. The average age of females and males did not differ significantly on t-testing. The results showed there were no statistically significant differences between mean values of Qx between phonatory tasks on ANOVA testing. However, the differences between mean values of % Irregularity were significantly different between tasks. The % Irregularity obtained for the phrase, was significantly different from the values obtained for the sustained vowels and single words. The values for the latter two did not differ significantly. The difference between male and female Qx and % Irregularity values were not significant on t-testing except for % Irregularity for the word 'Ola', which was greater in men. Our findings show that for calculation of Qx either sustained vowel phonation, single words or phrases may be used. % Irregularity of vocal fold vibration is however task dependent.

Adult↗

[Our experiences in microvascular reconstruction with free forearm skin flap].

Free forearm skin-fascia flap was used at 14 patients for head and neck reconstruction. Tissue defect was located in mesopharynx at 6 patients, in piriformis recessus at 2, in buccal mucosa at 1, in hypopharynx 4 and very large defect embracing mesopharynx, hard and soft palate at one patient. To present moment lives 11 ill in this one from recurrent diseases. Most important element of microvascular junction is correctly executed venous junction. Patients after microvascular flaps showed less percentage of early complications (fistulas, shorter time of staging in Clinic). Connection of partial operation of the larynx with microvascular reconstruction of throat creates chance on good oncological on functional result. Free forearm skin-fascia flap provides good anatomical and functional result after various reconstructions of head and neck region.

Female↗