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Biomedical subjects

Patrice Bourée

Publications and source records attributed to Patrice Bourée.

11 recordsLinked to original sources

[Parasite-induced hypereosinophilia].

Blood hypereosinophilia (eosinophilia count of more than 500 per microliter, i.e., 0.5.10(9)/L) is a laboratory finding that requires a careful workup. Review of the patient's medical history and clinical examination can usually rule out non-parasitic causes. Parasitic infections must be sought by examination of stool, urine, and blood examinations and by serological tests. These examinations, with special techniques for cosmopolitan and tropical parasites and for digestive or tissular parasites, must be repeated. Improvement of blood eosinophilia and of the serum antibody titers is one criterion of treatment effectiveness.

Antiparasitic Agents↗

[Epidemiology of tinea capitis. Five-year retrospective study in three hospitals in the Val de Marne].

OBJECTIVE: Describe the epidemiology of Tinea capitis in three hospitals in the Val de Marne (suburban district southeast of Paris) and evaluate the usefulness of screening the families of index cases. METHODS: The study included 3 hospitals: Henri Mondor Hospital, Creteil Intermunicipal Hospital Center and Bicêtre Hospital. Index patients had a positive culture for dermatophytes during visits to the mycology-dermatology or pediatric clinics from January 1998 through December 2002. The diagnostic procedure was identical in all centers. In two centers, scalp samples were taken routinely from family members, even in the absence of clinical lesions. Species were identified according to the phenotypic features of the cultures. We recorded the age, sex, and geographic origin of each patient, when available. RESULTS: Samples were obtained from 487 outpatients (including family members): 383 were positive (356 children under 16 years, 27 adults). Of the children with positive cultures, 214 were boys (60%); of the adults, 18 (66%) were women. Distribution of geographic origin was: sub-Saharan Africa (71%), Europe (10%), Caribbean (5%) and North Africa (4,7%). Species identification confirmed the predominance of anthropophilic species, with 46% of the isolates Trichophyton soudanense and 33% Microsporum langeronii. T. violaceum was reported in 5.5% of cases and T. tonsurans in 2.8%. M. canis (9%), found in 34 Europeans, was the main zoophilic species. Family screening accounted for 263 of the 487 outpatients. Of 242 children from 86 families, 153 (63%) had positive cultures. Of the 21 parents, 5 had a positive culture. Globally, the family screening identified 158 cases in 263 tests (60%). CONCLUSION: Tinea capitis in the Val de Marne is mainly due to anthropophilic species and involves children of African origin. The frequency of family contamination indicates that routine screening of family members of infected children is valuable.

Adolescent↗

Immunity and immunization in elderly.

As the average life expectancy increases, retired people want to travel. Five to 8% of travellers in tropical areas are old persons. Immune system suffers of old age as the other organs. The number and the functions of the T-lymphocytes decrease, but the B-lymphocytes are not altered. So, the response to the vaccinations is slower and lower in the elderly. Influenza is a great cause of death rate in old people. The seroconversion, after vaccine, is 50% from 60 to 70 years old, 31% from 70 to 80 years old, and only 11% after 80 years old. But in public health, the vaccination reduced the morbidity by 25%, admission to hospital by 20%, pneumonia by 50%, and mortality by 70%. Antipoliomyelitis vaccine is useful for travellers, as the vaccines against hepatitis and typhoid fever. Pneumococcal vaccine is effective in 60%. Tetanus is fatal in at last 32% of the people above 80 years, therefore this vaccine is very important.

Aged↗

Visceral larva migrans mimicking lymphoma.

We report a case of visceral larva migrans in an adult with fever, night sweats, weight loss, hilar and mediastinal lymphadenopathy, bilateral pleural effusion, and eosinophilia-mimicking lymphoma. Visceral larva migrans was diagnosed subsequently because of negative findings for malignancy and positive serologic test result for Toxocara canis. Progressive improvement was observed with albendazole therapy.

Aged↗

Delayed Salmonella bacteriuria in a patient infected with Schistosoma haematobium.

The authors report a case of Schistosoma haematobium infection with delayed occurrence of Salmonella bacteriuria following treatment of schistosomiasis. Standard models of interaction between these two pathogens may not be fully satisfactory in such a case of co-infection. The role played by a decreased host immune response following schistosomiasis may thus be highlighted to explain a delayed or prolonged infection with Salmonella.

Adult↗

[Leprosy in Haiti].

Leprosy has yet a great impact on public health in Haiti. A study was carried out in Haiti from 1977 to 1999. On 2,160 registered cases, mostly are paucibacillaries: 412 cases are under 15 year old patients and 1,306 more than 15 year old. Multibacillaries cases are 85 in under 15 year old patients and 357 in more than 15 year old. By the improvement of sanitary conditions, detecting cases and multidrug therapy, leprosy had decreased during these last years, with an incidence from 0.1 to 0.2%. However, with the increasing poverty and political disorders, the control of leprosy remains difficult in Haiti.

Adolescent↗

[Scorpion stings: a public health problem in Morelos (Mexico)].

Scorpion stings represent a major public health problem in Mexico. Their annual incidence is estimated at 150,000 cases; 800-1,000 people die from them each year, 72.5% of whom are children younger than 5 years old. The states most affected are Aguascalientes, Colima, Durango, Guanajuato, Guerrero, Jalisco, Michoacán, Morelos, Oaxaca, Puebla, Sinaloa, and Zacatecas. Morelos is an endemic zone, and scorpion stings are relatively frequent, but the indigenous population underestimates the risks. In this locality, scorpion stings lead to high morbidity, with an average of 10,219 cases each year, and a prevalence varying from 584.86 per 100,000 inhabitants in 1994 to 2043.3 per 100,000 inhabitants in 2003. Because of this upsurge, systematic medical supervision and serum therapy are necessary if scorpion poisoning is suspected in a child. The indigenous community as well as tourists visiting Mexico must be informed about the substantial risk of scorpion poisoning.

Adolescent↗