Biomedical subjects
Publications and source records attributed to P Zvandasara.
A case of ruptured ectopic and twin intra-uterine pregnancy is presented. The patient had conceived following ovulation induction with clomiphene citrate.
We assessed the sensitivity and specificity of a newly developed DNA PCR kit (Roche Diagnostic Corporation, Indianapolis, Ind.) that incorporates primers for all the group M viruses for the detection of human immunodeficiency virus (HIV) type 1 (HIV-1) infection in Zimbabwe. A total of 202 whole-blood samples from adults whose HIV status was known were studied. This included 100 HIV-1-positive and 102 HIV-1-negative samples selected on the basis of concordant results obtained with two enzyme-linked immunosorbent assay kits. The prototype Roche DNA PCR assay had a 100% sensitivity for the detection of HIV-1 DNA and a specificity of 100%. We conclude that the new Roche DNA PCR kit is accurate for the detection of HIV DNA in Zimbabwean samples, in which HIV-1 subtype C dominates.
The incidence of abdominal pregnancy is unknown at Harare Hospital. Four patients admitted to the Hospital in 1993 are presented. Diagnosis was difficult and at laparotomy the placenta, was left in situ in three patients.
Advanced extra-uterine pregnancy is rare, in the developed countries. They still contribute to a significant maternal morbidity in the developing countries. A review of the literature on the subject is presented. The management of the placenta is paramount, removal is recommended when it is safe for the patient. The morbidity is high in patients where the placenta is left in situ.(ABSTRACT TRUNCATED AT 250 WORDS)
Hydatidiform mole contributes to a significant numbers of hospital admissions at Harare Hospital. The characteristics, diagnosis, management and follow up of the women with molor pregnancy admitted to Harare Hospital are presented. The follow up of these women was grossly inadequate.
This article critically reviews the current understanding of the origin of hydatidiform mole. The pathogenesis, clinical presentation and diagnosis is discussed. Suction curettage and close patient follow up reduces the mortality and morbidity of the patients with this disease.
Explore the source record for details and available documents.